Myocardial Contrast Echocardiography in Congenital Heart Disease
Patients with congenital heart disease in whom the right ventricle is exposed to pressure or volume overload show progressive systolic dysfunction of the right ventricle, the fact of which conveys substantial morbidity and mortality. The aim of this study is to investigate the myocardial perfusion in these patients by myocardial contrast echocardiography (MCE) in order to determine whether disturbed blood flow plays a role in the development of right ventricular systolic dysfunction.
D-Transposition of Great Arteries
Tetralogy of Fallot
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||Quantification of the Myocardial Microcirculation by Contrast Echocardiography In Adult Patients With Congenital Heart Disease|
|Study Start Date:||August 2006|
|Study Completion Date:||December 2008|
|Primary Completion Date:||December 2008 (Final data collection date for primary outcome measure)|
The TGA group consists of 15 patients treated withMustard or Senning procedures for surgical repaired of D-TGA atrial switch operation.
The TOF group consists of 15 patients with surgically corrected TOF.
The control group C consists of 15 control subjects (AH) with normal Doppler Echocardiographic echocardiographic examinations.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00412685
|University Hospital Inselspital|
|Bern, Switzerland, 3010|
|Principal Investigator:||Christian Seiler, Prof.||University Hospital Berne, Switzerland|