ClinicalTrials.gov
ClinicalTrials.gov Menu

Insulin Resistance and Hypertensive Disorders in Pregnancy

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT00412230
Recruitment Status : Completed
First Posted : December 18, 2006
Last Update Posted : February 18, 2009
Sponsor:
Information provided by:
University of Messina

Brief Summary:
The purpose of this study is to determine whether insulin resistance might affect the pathogenesis of hypertensive disorders in pregnancy since midtrimester. Furthermore, markers of vascular and placental injuries, of oxidative stress and inflammation will be evaluated.

Condition or disease
Hypertension in Pregnancy Diabetes Mellitus in Pregnancy

Study Type : Observational
Estimated Enrollment : 100 participants
Observational Model: Case Control
Time Perspective: Retrospective
Official Title: The Role of Insulin Resistance in Gestational Hypertension and in Preeclampsia.
Study Start Date : October 2006
Actual Study Completion Date : June 2008

Resource links provided by the National Library of Medicine

Drug Information available for: Insulin

Group/Cohort
no treatment
2




Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years to 45 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
pregnant outpatients
Criteria

Inclusion Criteria:

  • PCOS, BMI>/=30
  • previous pregnancy affected by hypertension or gestational diabetes
  • thrombophilia
  • Type I or II diabetes mellitus
  • autoimmune diseases
  • twin pregnancy
  • renal diseases
  • previous pre-eclampsia in relatives

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00412230


Locations
Italy
University Hospital
Messina, Italy, 98121
Sponsors and Collaborators
University of Messina
Investigators
Principal Investigator: Rosario D'Anna, Associate Professor University of Messina

Responsible Party: Rosario D'Anna, University of Messina
ClinicalTrials.gov Identifier: NCT00412230     History of Changes
Other Study ID Numbers: 120254
First Posted: December 18, 2006    Key Record Dates
Last Update Posted: February 18, 2009
Last Verified: February 2009

Keywords provided by University of Messina:
Pre-eclampsia
Gestational diabetes
Insulin resistance
hypertension in pregnancy

Additional relevant MeSH terms:
Hypertension
Hypertension, Pregnancy-Induced
Pregnancy in Diabetics
Pregnancy Complications
Diabetes Mellitus
Insulin Resistance
Pre-Eclampsia
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases
Vascular Diseases
Cardiovascular Diseases
Hyperinsulinism
Insulin
Hypoglycemic Agents
Physiological Effects of Drugs