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Insulin Resistance and Hypertensive Disorders in Pregnancy

This study has been completed.
Information provided by:
University of Messina Identifier:
First received: December 15, 2006
Last updated: February 17, 2009
Last verified: February 2009
The purpose of this study is to determine whether insulin resistance might affect the pathogenesis of hypertensive disorders in pregnancy since midtrimester. Furthermore, markers of vascular and placental injuries, of oxidative stress and inflammation will be evaluated.

Hypertension in Pregnancy Diabetes Mellitus in Pregnancy

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Retrospective
Official Title: The Role of Insulin Resistance in Gestational Hypertension and in Preeclampsia.

Resource links provided by NLM:

Further study details as provided by University of Messina:

Estimated Enrollment: 100
Study Start Date: October 2006
Study Completion Date: June 2008
no treatment


Ages Eligible for Study:   18 Years to 45 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
pregnant outpatients

Inclusion Criteria:

  • PCOS, BMI>/=30
  • previous pregnancy affected by hypertension or gestational diabetes
  • thrombophilia
  • Type I or II diabetes mellitus
  • autoimmune diseases
  • twin pregnancy
  • renal diseases
  • previous pre-eclampsia in relatives
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Please refer to this study by its identifier: NCT00412230

University Hospital
Messina, Italy, 98121
Sponsors and Collaborators
University of Messina
Principal Investigator: Rosario D'Anna, Associate Professor University of Messina
  More Information

Responsible Party: Rosario D'Anna, University of Messina Identifier: NCT00412230     History of Changes
Other Study ID Numbers: 120254
Study First Received: December 15, 2006
Last Updated: February 17, 2009

Keywords provided by University of Messina:
Gestational diabetes
Insulin resistance
hypertension in pregnancy

Additional relevant MeSH terms:
Hypertension, Pregnancy-Induced
Pregnancy in Diabetics
Pregnancy Complications
Diabetes Mellitus
Insulin Resistance
Vascular Diseases
Cardiovascular Diseases
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases
Hypoglycemic Agents
Physiological Effects of Drugs processed this record on September 21, 2017