Functional Magnetic Resonance Imaging - Synthetic Aperture Magnetometry (fMRI-SAM) and Alzheimer's Disease
![]() |
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. |
ClinicalTrials.gov Identifier: NCT00412048 |
Recruitment Status
:
Withdrawn
First Posted
: December 15, 2006
Last Update Posted
: November 14, 2012
|
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
Condition or disease | Intervention/treatment | Phase |
---|---|---|
Alzheimer's Disease | Procedure: fMRI to detect MCI patients who will convert to Alzheimer's disease | Not Applicable |
Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 0 participants |
Allocation: | Non-Randomized |
Intervention Model: | Single Group Assignment |
Masking: | None (Open Label) |
Primary Purpose: | Diagnostic |
Official Title: | Evaluation of fMRI-SAM in the Early Detection of Alzheimer's Disease. |
Study Start Date : | April 2012 |
Estimated Primary Completion Date : | February 2018 |
Estimated Study Completion Date : | February 2018 |

Arm | Intervention/treatment |
---|---|
ALZHEIMER DISEASE |
Procedure: fMRI to detect MCI patients who will convert to Alzheimer's disease
There is a fMRI to be realized in the 3 arms. No drug is administered
|
MOLD COGNITIVE IMPAIRMENT |
Procedure: fMRI to detect MCI patients who will convert to Alzheimer's disease
There is a fMRI to be realized in the 3 arms. No drug is administered
|
CONTROLS |
Procedure: fMRI to detect MCI patients who will convert to Alzheimer's disease
There is a fMRI to be realized in the 3 arms. No drug is administered
|
- Comparing fMRI data between 3 groups of subjects: MCI, Alzheimer's disease and normal subjects [ Time Frame: 1, 5 years ]
- Follow-up of MCI patients at 6, 12 and 18 months to detect a conversion to Alzheimer's disease [ Time Frame: Prediction of Alzheimer's disease on fMRI data ]

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study: | 55 Years to 75 Years (Adult, Senior) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | Yes |
Inclusion criteria:
- Alzheimer's disease of mild to moderate severity (25 patients)
- Amnestic MCI patients (25 patients)
- 55-75 year-old patients
Exclusion criteria:
- Any other cause of dementia for AD patients
- Any stroke
- Any disease with a negative vital prognosis

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00412048
Principal Investigator: | Francois Sellal, MD | Hôpitaux Universitaires de Strasbourg |
Responsible Party: | University Hospital, Strasbourg, France |
ClinicalTrials.gov Identifier: | NCT00412048 History of Changes |
Other Study ID Numbers: |
3659 |
First Posted: | December 15, 2006 Key Record Dates |
Last Update Posted: | November 14, 2012 |
Last Verified: | November 2012 |
Additional relevant MeSH terms:
Alzheimer Disease Dementia Brain Diseases Central Nervous System Diseases Nervous System Diseases |
Tauopathies Neurodegenerative Diseases Neurocognitive Disorders Mental Disorders |