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Endometrial Sampling (Pipelle)in IVF Patients

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified December 2006 by Sheba Medical Center.
Recruitment status was:  Recruiting
Information provided by:
Sheba Medical Center Identifier:
First received: December 12, 2006
Last updated: NA
Last verified: December 2006
History: No changes posted
A prospective cross-over randomized study aimed to test the hypothesis that local injury of the endometrium increases the implantation rate in the successive cycle. Seventy IVF patients will be randomly selected to undergo either endometrial biopsies or minimal cervical scratch on days 8-10 and 21-23 of their cycle, preceding the IVF treatment. If not pregnant, the women will continue for another IVF cycle, preceded by endometrial or cervical scratch complimentary to their procedure in the first cycle. The main major outcomes will include pregnancy rate, implantation rate, endometrial thickness, abortion rate, live births and embryo quality.

Condition Intervention
Infertility Procedure: Pipelle (Endometrial Sampling)

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single
Primary Purpose: Treatment
Official Title: Endometrial Sampling (Pipelle)in IVF Patients

Further study details as provided by Sheba Medical Center:

Estimated Enrollment: 70

Ages Eligible for Study:   20 Years to 45 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Women undergoing IVF treatment
  • Repeated Implantation failure

Exclusion Criteria:

  • PID or suspected PID
  • Undiagnosed Irregular Bleeding
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00411021

Contact: Micha Baum, MD

IVF Unit, Sheba Medical Center Recruiting
Ramat-Gan, Israel, 52621
Contact: Micha Baum, MD   
Sponsors and Collaborators
Sheba Medical Center
Principal Investigator: Micha Baum, MD Sheba Medical Center, Israel
  More Information Identifier: NCT00411021     History of Changes
Other Study ID Numbers: SHEBA-05-3674-MB-CTIL
Study First Received: December 12, 2006
Last Updated: December 12, 2006

Additional relevant MeSH terms:
Genital Diseases, Male
Genital Diseases, Female processed this record on August 21, 2017