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Trial record 1 of 1 for:    NCT00409201
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Reboxetine Adjuvant Therapy for the Treatment of Schizophrenia

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified March 2006 by Abarbanel Mental Health Center.
Recruitment status was:  Recruiting
Information provided by:
Abarbanel Mental Health Center Identifier:
First received: December 7, 2006
Last updated: NA
Last verified: March 2006
History: No changes posted
30 patients will randomly be selected and will be administered either reboxetine or a placebo. changes in cognition and behavior will be assessed by computer tests and scales during a six week study period.

Condition Intervention Phase
Schizophrenia Drug: reboxetine adjuvant therapy Phase 1

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Double
Primary Purpose: Treatment
Official Title: Phase 1 Study of Reboxetine Adjuvant Therapy and Cognitive and Behavioral Measures

Resource links provided by NLM:

Further study details as provided by Abarbanel Mental Health Center:

Primary Outcome Measures:
  • sans, panss, hamilton, ham-a, calgary, physical examination, cogscan test

Secondary Outcome Measures:
  • esrs, progesterom, sexual functioning, covy, cgi, cgi improved

Estimated Enrollment: 30
Study Start Date: March 2006
Estimated Study Completion Date: November 2006
Detailed Description:
all participants will be administered panss, sans, esrs, calgary, progesterom, sexual functioning scale, ham-a, covy, hamilton depression scale, and cgi and cgi improved rating on the first visit, as well as blood tests, ecg and weight. they will then be tested using a computer cognitive test (cogscan test) that lasts about 45 minutes. next, they will be given either a two week dose of placebo or treatment (2 mg * 2 daily for first week, then 4 mg. day, 2 mg. night for the second week). after two weeks they the dose is increased to 4 mg. * 2 daily. at four weeks all tests are readministered, as well as at six weeks. the study is concluded at 6 weeks, following a readministration of tests. physical examination is also administered at the conclusion.

Ages Eligible for Study:   18 Years to 65 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • schizophrenia all types
  • 18>

Exclusion Criteria:

  • uti
  • >65
  • non organic state
  • no depression treatment
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00409201

Contact: stanislav baranchik, md 972-3-5552625

Abarbanel Medical Mental Health Center Recruiting
Bat Yam, Israel, 59100
Contact: stanislav baranchik, md    972-3-5552625      
Contact: alex aviv, md    972-3-552703   
Principal Investigator: stanislav baranchik, md         
Abarbanel Medical Mental Health Center Recruiting
Bat Yam, Israel, 59100
Principal Investigator: stanislav baranchik, md         
Sponsors and Collaborators
Abarbanel Mental Health Center
Principal Investigator: stanislav baranchik, md abarbanel mhc
  More Information

Publications: Identifier: NCT00409201     History of Changes
Other Study ID Numbers: 284
Study First Received: December 7, 2006
Last Updated: December 7, 2006

Keywords provided by Abarbanel Mental Health Center:

Additional relevant MeSH terms:
Schizophrenia Spectrum and Other Psychotic Disorders
Mental Disorders
Antidepressive Agents
Psychotropic Drugs
Adrenergic Uptake Inhibitors
Neurotransmitter Uptake Inhibitors
Membrane Transport Modulators
Molecular Mechanisms of Pharmacological Action
Adrenergic Agents
Neurotransmitter Agents
Physiological Effects of Drugs processed this record on August 23, 2017