Investigation of Genetic Risk of Metabolic Syndrome in Company Employee (NGK Study)

The recruitment status of this study is unknown because the information has not been verified recently.
Verified September 2007 by Nagoya University.
Recruitment status was  Recruiting
Information provided by:
Nagoya University Identifier:
First received: December 6, 2006
Last updated: September 19, 2007
Last verified: September 2007
The metabolic syndrome is a highly prevalent disorder, which causes atherosclerotic cardiovascular disease and is closely associated with insulin resistance. The alteration of the secretion of adipocytokines from accumulated visceral adipose tissue in the obese induces insulin resistance. The purpose of this study is to identify gene polymorphisms that confer susceptibility to the metabolic syndrome and to make up a new health guidance program based on genetic risk assessment. About 25% of male employees over 45 years old in a certain company are diagnosed with the metabolic syndrome in medical examination. We, the researchers at Nagoya University, will analyze gene polymorphism and various biomarkers of over 3500 company employees.

Metabolic Syndrome X
Diabetes Mellitus

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Longitudinal
Official Title: Assessment of Genetic Risk of Metabolic Syndrome in Company Employee and Making New Health Guidance Program (NGK Study)

Resource links provided by NLM:

Further study details as provided by Nagoya University:

Estimated Enrollment: 4000
Study Start Date: September 2006

Ages Eligible for Study:   20 Years to 65 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Healthy subjects who work for a certain company
  Contacts and Locations
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Please refer to this study by its identifier: NCT00408824

Contact: Kenji Yasui, MD, PhD +81-52-788-6211

Department of Bio-information Analysis, Research Institute of Environmental Medicine, Nagoya University Recruiting
Nagoya, Aichi, Japan, 464-8601
Contact: Kenji Yasui, MD, PhD    +81-52-788-6211   
Principal Investigator: Kenji Yasui, MD, PhD         
Sponsors and Collaborators
Nagoya University
Study Chair: Kenji Yasui, MD, PhD Department of Bio-information Analysis, Research Institute of Environmental Medicine, Nagoya University
  More Information

Publications automatically indexed to this study by Identifier (NCT Number): Identifier: NCT00408824     History of Changes
Other Study ID Numbers: RIEM-G-3 
Study First Received: December 6, 2006
Last Updated: September 19, 2007
Health Authority: Japan: Ministry of Education, Culture, Sports, Science and Technology

Keywords provided by Nagoya University:
insulin resistance
Metabolic syndrome

Additional relevant MeSH terms:
Metabolic Syndrome X
Glucose Metabolism Disorders
Insulin Resistance
Lipid Metabolism Disorders
Metabolic Diseases
Pathologic Processes processed this record on May 23, 2016