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Investigation of Genetic Risk of Metabolic Syndrome in Company Employee (NGK Study)

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ClinicalTrials.gov Identifier: NCT00408824
Recruitment Status : Unknown
Verified September 2007 by Nagoya University.
Recruitment status was:  Recruiting
First Posted : December 7, 2006
Last Update Posted : September 20, 2007
Sponsor:
Information provided by:
Nagoya University

Brief Summary:
The metabolic syndrome is a highly prevalent disorder, which causes atherosclerotic cardiovascular disease and is closely associated with insulin resistance. The alteration of the secretion of adipocytokines from accumulated visceral adipose tissue in the obese induces insulin resistance. The purpose of this study is to identify gene polymorphisms that confer susceptibility to the metabolic syndrome and to make up a new health guidance program based on genetic risk assessment. About 25% of male employees over 45 years old in a certain company are diagnosed with the metabolic syndrome in medical examination. We, the researchers at Nagoya University, will analyze gene polymorphism and various biomarkers of over 3500 company employees.

Condition or disease
Healthy Metabolic Syndrome X Hyperlipidemia Hypertension Diabetes Mellitus

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Study Type : Observational
Estimated Enrollment : 4000 participants
Observational Model: Case-Control
Time Perspective: Other
Official Title: Assessment of Genetic Risk of Metabolic Syndrome in Company Employee and Making New Health Guidance Program (NGK Study)
Study Start Date : September 2006

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Ages Eligible for Study:   20 Years to 65 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Healthy subjects who work for a certain company

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00408824


Contacts
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Contact: Kenji Yasui, MD, PhD +81-52-788-6211 kenji@riem.nagoya-u.ac.jp

Locations
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Japan
Department of Bio-information Analysis, Research Institute of Environmental Medicine, Nagoya University Recruiting
Nagoya, Aichi, Japan, 464-8601
Contact: Kenji Yasui, MD, PhD    +81-52-788-6211    kenji@riem.nagoya-u.ac.jp   
Principal Investigator: Kenji Yasui, MD, PhD         
Sponsors and Collaborators
Nagoya University
Investigators
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Study Chair: Kenji Yasui, MD, PhD Department of Bio-information Analysis, Research Institute of Environmental Medicine, Nagoya University
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
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ClinicalTrials.gov Identifier: NCT00408824    
Other Study ID Numbers: RIEM-G-3
First Posted: December 7, 2006    Key Record Dates
Last Update Posted: September 20, 2007
Last Verified: September 2007
Keywords provided by Nagoya University:
insulin resistance
adipocytokine
Metabolic syndrome
Diabetes
Additional relevant MeSH terms:
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Metabolic Syndrome
Hyperlipidemias
Syndrome
Disease
Pathologic Processes
Insulin Resistance
Hyperinsulinism
Glucose Metabolism Disorders
Metabolic Diseases
Dyslipidemias
Lipid Metabolism Disorders