Hypnosis for Treating Xerostomia Following Radiotherapy in Head & Neck Cancer Patients

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00408759
Recruitment Status : Unknown
Verified December 2006 by Bnai Zion Medical Center.
Recruitment status was:  Recruiting
First Posted : December 7, 2006
Last Update Posted : December 7, 2006
Information provided by:
Bnai Zion Medical Center

Brief Summary:

xerostomia develops in all patients with head and neck cancer following radiotherapy. it consists one of the main side effects which affects quality of life. currently, there is no standard of care for treating this condition. parasympathomimetic drugs may help but carry significant side effects.

hypnosis may affect autonomic function such as salivation, in healthy this study we will explore the efficacy of hypnosis in improving salivation, in the patient population.

Condition or disease Intervention/treatment Phase
Xerostomia Behavioral: hypnosis Phase 2

Detailed Description:
10 head and neck cancer patients with xerostomia following radiotherapy will be assessed for severity of xerostomia using questionnares and quantitative salivation tests. patients responsive to citric acid will receive a hypnotic session with specific suggestion for salivation. saliva volume will be assessed pre and post hypnosis. patients will receive a CD with recorded hypnotic session to use freely at home. xerostomia will be assessed using a questionnare one week following hypnosis.

Study Type : Interventional  (Clinical Trial)
Enrollment : 10 participants
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Phase 2 Study of Hypnosis for Treating Xerostomia Following Radiotherapy in Head & Neck Cancer Patients
Study Start Date : November 2006
Study Completion Date : December 2006

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Dry Mouth

Primary Outcome Measures :
  1. salivaa volume
  2. quality of life related to salivation

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • radiotherapy for head and neck cancer
  • xerostomia

Exclusion Criteria:

  • psychiatric illness (present or past)

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00408759

Contact: elad schiff 972482654767
Contact: gorge mogilner 97248359359

bnai zion MC Recruiting
Haifa, Israel
Contact: elad schiff    97248359767   
Sub-Investigator: Gorge Mogilner         
Sub-Investigator: Noam Yarom         
Sub-Investigator: Ilana Dowek         
Sponsors and Collaborators
Bnai Zion Medical Center
Principal Investigator: Elad Schiff Bnai Zion MC Identifier: NCT00408759     History of Changes
Other Study ID Numbers: eschiff
First Posted: December 7, 2006    Key Record Dates
Last Update Posted: December 7, 2006
Last Verified: December 2006

Keywords provided by Bnai Zion Medical Center:
dry mouth
head and neck cancer

Additional relevant MeSH terms:
Head and Neck Neoplasms
Neoplasms by Site
Salivary Gland Diseases
Mouth Diseases
Stomatognathic Diseases