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Smoking Cessation in Substance Abuse Treatment Patients: A Feasibility Study

This study has been completed.
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Information provided by (Responsible Party):
UConn Health Identifier:
First received: December 4, 2006
Last updated: November 17, 2011
Last verified: November 2011
The purpose of this study is to compare the effects of self-help materials for smoking cessation and self-help materials for smoking cessation plus prize-based contingency management (CM), in which prize incentives are available for breath and saliva samples that indicate smoking abstinence, in substance abuse treatment patients who want to quit smoking.

Condition Intervention Phase
Nicotine Dependence Behavioral: Contingency Management Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Smoking Cessation in Substance Abuse Treatment Patients: A Feasibility Study

Resource links provided by NLM:

Further study details as provided by UConn Health:

Primary Outcome Measures:
  • Percent negative CO readings
  • Percent negative cotinine readings
  • Longest period of continuous abstinence

Secondary Outcome Measures:
  • Self-reported frequency and severity of smoking
  • Objective substance use
  • Self-reported substance use
  • Treatment retention

Enrollment: 80
Study Start Date: January 2004
Study Completion Date: March 2007
Primary Completion Date: March 2007 (Final data collection date for primary outcome measure)
Detailed Description:
The specific aims of this study are: (1) to examine the efficacy of self-help materials compared to self-help materials plus prize contingency management (CM) for smoking abstinence in substance abuse treatment patients and (2) examine the effects of smoking abstinence on substance use and substance treatment retention. To address these specific aims, cigarette smokers entering treatment for alcohol, cocaine or heroin abuse or dependence, who report daily smoking (at least one cigarette per day) for the past year, and who meet other inclusion and exclusion criteria, are randomly assigned to receive self-help materials or self-help materials plus CM. Individuals in the CM group have the opportunity to win prizes, worth on average $1, $20, or $100, when they meet smoking abstinence criteria (CO < 8ppm and salivary cotinine < 10ng/mL). Participants meet with research staff 4 times/week during Weeks 1-4, 2 times/week during Weeks 5-8 and 1 time/week during Weeks 9-12. Follow-up interviews are scheduled 1, 3 and 6 months following the smoking quit date.

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • meets diagnostic criteria for alcohol, cocaine or heroin abuse or dependence
  • self-report daily smoking for at least the past year
  • CO > 8ppm
  • interested in quitting smoking while in treatment,
  • minimum age 18 years old
  • willing to provide names, addresses and phone numbers of individuals to assist in locating the patient for follow-up evaluations
  • English speaking

Exclusion Criteria:

  • current use of NRT
  • current use of bupropion
  • serious, uncontrolled psychiatric illness (e.g., acute schizophrenia, suicide risk)
  • dementia (Mini-mental status score of <23)
  • currently participating in another CM study at the clinic
  • in recovery for pathological gambling
  Contacts and Locations
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Please refer to this study by its identifier: NCT00408265

United States, Connecticut
University of Connecticut Health Center
Farmington, Connecticut, United States, 06030
Sponsors and Collaborators
UConn Health
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Principal Investigator: Sheila M Alessi, PhD UConn Health
  More Information

Responsible Party: UConn Health Identifier: NCT00408265     History of Changes
Other Study ID Numbers: NIAAA-ALE-03510
NIH Grant P50-AA03510
Study First Received: December 4, 2006
Last Updated: November 17, 2011

Keywords provided by UConn Health:
Nicotine Dependence
Contingency Management

Additional relevant MeSH terms:
Substance-Related Disorders
Tobacco Use Disorder
Chemically-Induced Disorders
Mental Disorders processed this record on August 16, 2017