Intravitreal Bevacizumab for Inflammatory Neovascular Membranes

This study has been completed.

Sponsor:

Information provided by:

Asociación para Evitar la Ceguera en México

ClinicalTrials.gov Identifier:

NCT00407121

First received: December 1, 2006

Last updated: NA

Last verified: December 2006

History: No changes posted

Purpose

Intravitreal injection of Bevacizumab in patients with Neovascular Membranes secondary to intraocular inflammation. We injected a single injection of Bevacizumab (2.5 mg/0.1 ml) and evaluate visual acuity , Fluorescein angiogram and retinal thickness by Optical Coherence Tomography (OCT) in 4 patients with Vogt Koyanagi Harada disease, 1 patient with Serpiginous Choroidopathy and 1 patient with Multifocal Choroiditis.

Condition	Intervention	Phase
Vogt Koyanagi Harada Disease Serpiginous Choroiditis Multifocal Choroiditis	Drug: Bevacizumab Procedure: Intravitreal Injection of Bevacizumab	Phase 3


Study Type:	Interventional
Study Design:	Allocation: Non-Randomized Intervention Model: Single Group Assignment Masking: Open Label Primary Purpose: Treatment
Official Title:	Intravitreal Bevacizumab for the Treatment of Neovascular Membranes in Patients With Intraocular Inflammation

Resource links provided by NLM:

Drug Information available for: Bevacizumab

Genetic and Rare Diseases Information Center resources: Vogt-Koyanagi-Harada Disease Multifocal Choroiditis Choroiditis Serpiginous Choroiditis Uveal Diseases Panuveitis

U.S. FDA Resources

Further study details as provided by Asociación para Evitar la Ceguera en México:

Primary Outcome Measures:

Best corrected visual acuity
Retinal thickness by OCT
Leakage in Fluorescein angiogram


Study Start Date:	August 2006
Estimated Study Completion Date:	November 2006

Eligibility


Ages Eligible for Study:	25 Years to 60 Years (Adult)
Sexes Eligible for Study:	All
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Clinical Diagnose
Patient Consent
Chronic stage of inflammation

Exclusion Criteria:

only eye
age lower than 30 yo.
Systemic condition

Contacts and Locations

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00407121

Locations


Mexico
Asociacion para Evitar la Ceguera en Mexico
Mexico, Distrito Federal, Mexico, 04030

Sponsors and Collaborators

Asociación para Evitar la Ceguera en México

Investigators


Principal Investigator:	Veronica Kon-Jara, MD	Asociación para Evitar la Ceguera en México
Study Chair:	LuzElena Concha-Del Rio, MD	Asociación para Evitar la Ceguera en México

More Information


ClinicalTrials.gov Identifier:	NCT00407121 History of Changes
Other Study ID Numbers:	APEC-0025
Study First Received:	December 1, 2006
Last Updated:	December 1, 2006

Keywords provided by Asociación para Evitar la Ceguera en México:


Neovascular Membrane Uveitis Bevacizumab

Additional relevant MeSH terms:


Uveomeningoencephalitic Syndrome Choroiditis Autoimmune Diseases of the Nervous System Nervous System Diseases Uveitis Uveal Diseases Eye Diseases Autoimmune Diseases Immune System Diseases Choroid Diseases	Uveitis, Posterior Panuveitis Bevacizumab Angiogenesis Inhibitors Angiogenesis Modulating Agents Growth Substances Physiological Effects of Drugs Growth Inhibitors Antineoplastic Agents

ClinicalTrials.gov processed this record on June 27, 2017

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