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Melanoma Inhibitory Activity (MIA): A Serological Marker for Metastatic Uveal Melanoma

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified November 2006 by Ludwig-Maximilians - University of Munich.
Recruitment status was:  Recruiting
Sponsor:
ClinicalTrials.gov Identifier:
NCT00406900
First Posted: December 4, 2006
Last Update Posted: December 6, 2006
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
Ludwig-Maximilians - University of Munich
  Purpose
Uveal Melanoma is the most common primary intraocular tumor in adults. Most tumors metastasize to the liver. So far no sensitive or specific serological tumor marker is routinely used. The marker "Melanoma inhibitory activity" is a promising marker. Study hypothesis is to detect metastatic lesions in an early stage. This would increase life expectance of our patients

Condition Intervention
Melanoma Radiotherapy Metastatic Disease Procedure: Treatment of metastatic disease

Study Type: Observational
Study Design: Observational Model: Defined Population
Primary Purpose: Screening
Time Perspective: Longitudinal
Time Perspective: Prospective

Resource links provided by NLM:


Further study details as provided by Ludwig-Maximilians - University of Munich:

Estimated Enrollment: 560
Study Start Date: January 1999
Estimated Study Completion Date: September 2006
Detailed Description:
Serum is taken from each melanoma patient at every follow up after signed concent. With ELISA the marker MIA is evaluated. An increase of MIA serum level will lead to search for metastasis by oncologists.
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • uveal melanoma (With/without overt metastatic disease)
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00406900


Contacts
Contact: Ulrich C Schaller, MD +49/89/5160 ext 3811 ulrich.schaller@med.uni-muenchen.de

Locations
Germany
Dept of Ophthalmology, University of Munich Recruiting
Munich, Germany, 80538
Contact: Ulrich C Schaller, MD    +49895160 ext 3811    ulrich.schaller@med.uni-muenchen.de   
Principal Investigator: Ulrich C Schaller, MD         
Sponsors and Collaborators
Ludwig-Maximilians - University of Munich
Investigators
Principal Investigator: Ulrich C Schaller, MD University of Munich, Germany
  More Information

Publications:
ClinicalTrials.gov Identifier: NCT00406900     History of Changes
Other Study ID Numbers: MIA
First Submitted: November 29, 2006
First Posted: December 4, 2006
Last Update Posted: December 6, 2006
Last Verified: November 2006

Keywords provided by Ludwig-Maximilians - University of Munich:
uveal melanoma
metastatic disease

Additional relevant MeSH terms:
Melanoma
Neoplasm Metastasis
Neoplasms, Second Primary
Neuroendocrine Tumors
Neuroectodermal Tumors
Neoplasms, Germ Cell and Embryonal
Neoplasms by Histologic Type
Neoplasms
Neoplasms, Nerve Tissue
Nevi and Melanomas
Neoplastic Processes
Pathologic Processes