Efficacy of Retreatments With Intravitreal Bevacizumab
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ClinicalTrials.gov Identifier: NCT00406744
Recruitment Status : Unknown
Verified November 2006 by Asociación para Evitar la Ceguera en México. Recruitment status was: Recruiting
Choroidal neovascularization is a leading cause of visual loss in people older than 60 years and for its treatment there had been performed multicentric studies with Lucentis (Ranibizumab) with a significant improval of visual acuity. In our institution we evaluated efficacy of bevacizumab in several pathologies but we dont know what would be the results if we use the same dose several times. Our purpose was to determine the efficacy of bevacizumab for improve or stabilize visual acuity with two or more intravitreal inyections of bevacizumab.
Condition or disease
Age Related Macular DegenerationChoroidal Neovascularization
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Ages Eligible for Study:
60 Years to 95 Years (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
* Any visual acuity
OCT: Central foveal thickness greater than 300 u or with evidence of subretinal fluid.
Active angiogram leakage
* Basal Inflammatory disease
Lesions bigger than 5400 u or with scarring greater than 50% of lesion.