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Comparison of Scheimpflug Photos of the Crystalline Lens in Patients Who Have Undergone Vitrectomy Surgery and Controls

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Rhonda Weeks, Barnes Retina Institute
ClinicalTrials.gov Identifier:
NCT00406263
First received: November 30, 2006
Last updated: July 25, 2016
Last verified: July 2016
  Purpose
Progression of nuclear sclerotic cataract after pars plana vitrectomy has been recognized for many years The mechanism for the rapid progression of nuclear sclerotic cataract remains unclear. The objective of this trial is to evaluate and compare the level and progression of cataract advancement in controls versus eyes that have undergone 20-gauge pars plana vitrectomy and 25-gauge pars plana vitrectomy.

Condition Intervention
Nuclear Sclerotic Cataract
Procedure: Scheimpflug crystalline lens photographs

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Comparison of Scheimpflug Photos of the Crystalline Lens in Patients Who Have Undergone Vitrectony Surgery and Controls

Resource links provided by NLM:


Further study details as provided by Barnes Retina Institute:

Enrollment: 49
Study Start Date: November 2006
Study Completion Date: October 2010
Primary Completion Date: October 2010 (Final data collection date for primary outcome measure)
Intervention Details:
    Procedure: Scheimpflug crystalline lens photographs
    scheimpflug photographs
Detailed Description:
Approximately 105 patients will be recruited to obtain 35 control eyes that have not had pars plana vitrectomy and 35 eyes who will have undergone 20-gauge pars plana vitrectomy and 35 eyes will have undergone 25-gauge pars plana vitrectomy. Scheimpflug crystalline lens photographs will be taken for evaluation of level and progression of cataract development.
  Eligibility

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
patients undergoing vitrectony surgery and controls
Criteria

Inclusion Criteria:

  • phakic eyes of patients that are scheduled to undergo pars plana vitrectomy,
  • controls will be phakic eyes of patients that have not undergone andy kind of intraocular surgery,
  • age 18 and older

Exclusion Criteria:

  • any eye that is pseudophakic,
  • has had previous vitreoretinal surgery,
  • has had previous intravitreal injection,
  • previous intraocular inflammatory condition such as uveitis,
  • previous irradiation,
  • any patient with a history of ocular malignancy,
  • history of infectious intraocular condition
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00406263

Locations
United States, Missouri
Barnes Retina Institute
St. Louis, Missouri, United States, 63110
Sponsors and Collaborators
Barnes Retina Institute
Investigators
Principal Investigator: Nancy M Holekamp, MD Barnes Retina Institute
  More Information

Responsible Party: Rhonda Weeks, Nancy Holekamp, MD, Principal Investigator, Barnes Retina Institute
ClinicalTrials.gov Identifier: NCT00406263     History of Changes
Other Study ID Numbers: 06-1016 
Study First Received: November 30, 2006
Last Updated: July 25, 2016
Health Authority: United States: Institutional Review Board

Keywords provided by Barnes Retina Institute:
nuclear sclerotic cataract
cataract

Additional relevant MeSH terms:
Cataract
Sclerosis
Lens Diseases
Eye Diseases
Pathologic Processes

ClinicalTrials.gov processed this record on September 28, 2016