We updated the design of this site on December 18, 2017. Learn more.
ClinicalTrials.gov
ClinicalTrials.gov Menu

Comparison of Scheimpflug Photos of the Crystalline Lens in Patients Who Have Undergone Vitrectomy Surgery and Controls

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT00406263
Recruitment Status : Completed
First Posted : December 4, 2006
Last Update Posted : July 27, 2016
Sponsor:
Information provided by (Responsible Party):
Rhonda Weeks, Barnes Retina Institute

Brief Summary:
Progression of nuclear sclerotic cataract after pars plana vitrectomy has been recognized for many years The mechanism for the rapid progression of nuclear sclerotic cataract remains unclear. The objective of this trial is to evaluate and compare the level and progression of cataract advancement in controls versus eyes that have undergone 20-gauge pars plana vitrectomy and 25-gauge pars plana vitrectomy.

Condition or disease Intervention/treatment
Nuclear Sclerotic Cataract Procedure: Scheimpflug crystalline lens photographs

Detailed Description:
Approximately 105 patients will be recruited to obtain 35 control eyes that have not had pars plana vitrectomy and 35 eyes who will have undergone 20-gauge pars plana vitrectomy and 35 eyes will have undergone 25-gauge pars plana vitrectomy. Scheimpflug crystalline lens photographs will be taken for evaluation of level and progression of cataract development.

Study Type : Observational
Actual Enrollment : 49 participants
Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Comparison of Scheimpflug Photos of the Crystalline Lens in Patients Who Have Undergone Vitrectony Surgery and Controls
Study Start Date : November 2006
Primary Completion Date : October 2010
Study Completion Date : October 2010

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Cataract
U.S. FDA Resources


Intervention Details:
    Procedure: Scheimpflug crystalline lens photographs
    scheimpflug photographs



Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
patients undergoing vitrectony surgery and controls
Criteria

Inclusion Criteria:

  • phakic eyes of patients that are scheduled to undergo pars plana vitrectomy,
  • controls will be phakic eyes of patients that have not undergone andy kind of intraocular surgery,
  • age 18 and older

Exclusion Criteria:

  • any eye that is pseudophakic,
  • has had previous vitreoretinal surgery,
  • has had previous intravitreal injection,
  • previous intraocular inflammatory condition such as uveitis,
  • previous irradiation,
  • any patient with a history of ocular malignancy,
  • history of infectious intraocular condition

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00406263


Locations
United States, Missouri
Barnes Retina Institute
St. Louis, Missouri, United States, 63110
Sponsors and Collaborators
Barnes Retina Institute
Investigators
Principal Investigator: Nancy M Holekamp, MD Barnes Retina Institute

Responsible Party: Rhonda Weeks, Nancy Holekamp, MD, Principal Investigator, Barnes Retina Institute
ClinicalTrials.gov Identifier: NCT00406263     History of Changes
Other Study ID Numbers: 06-1016
First Posted: December 4, 2006    Key Record Dates
Last Update Posted: July 27, 2016
Last Verified: July 2016

Keywords provided by Rhonda Weeks, Barnes Retina Institute:
nuclear sclerotic cataract
cataract

Additional relevant MeSH terms:
Cataract
Sclerosis
Lens Diseases
Eye Diseases
Pathologic Processes