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Cyclosporine A in the Treatment of Juvenile Idiopathic Arthritis (JIA) Associated Chronic Anterior Uveitis

This study has been completed.
Information provided by:
St. Franziskus Hospital Identifier:
First received: November 27, 2006
Last updated: June 2, 2009
Last verified: June 2009
Juvenile idiopathic arthritis (JIA) is often associated with chronic anterior uveitis. Presence of vision threatening complications may indicate immunosuppressive therapy. In this study, the experience with cyclosporine A (CsA) as mono- or combination-therapy is analyzed.

Condition Intervention
Uveitis Juvenile Idiopathic Arthritis Drug: Cyclosporine A

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Efficacy and Adverse Effects of Cyclosporine A in the Treatment of Chronic Anterior Uveitis in Patients With Juvenile Idiopathic Arthritis

Resource links provided by NLM:

Further study details as provided by St. Franziskus Hospital:

Estimated Enrollment: 60
Study Start Date: January 1991
Estimated Study Completion Date: August 2006

Ages Eligible for Study:   up to 16 Years   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
patients with JIA and cyclosporin A therapy

Inclusion Criteria:

  • uveitis
  • JIA
  Contacts and Locations
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Please refer to this study by its identifier: NCT00404482

Deutsches Zentrum für Kinder- und Jugendrheumatologie
Garmisch-Partenkirchen, Germany
Department of Ophthalmology at St.-FranziskusHospital
Münster, Germany
Kinder und Jugendrheumatologie St. Josef Stift
Sendenhorst, Germany
Sponsors and Collaborators
St. Franziskus Hospital
Principal Investigator: Christoph Tappeiner, MD Department of Ophthalmology at University Bern - Inselspital
  More Information Identifier: NCT00404482     History of Changes
Other Study ID Numbers: 01-1106
Study First Received: November 27, 2006
Last Updated: June 2, 2009

Keywords provided by St. Franziskus Hospital:
Cyclosporine A

Additional relevant MeSH terms:
Arthritis, Juvenile
Uveitis, Anterior
Joint Diseases
Musculoskeletal Diseases
Uveal Diseases
Eye Diseases
Rheumatic Diseases
Connective Tissue Diseases
Autoimmune Diseases
Immune System Diseases
Iris Diseases
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Immunosuppressive Agents
Immunologic Factors
Physiological Effects of Drugs
Antifungal Agents
Anti-Infective Agents
Dermatologic Agents
Antirheumatic Agents
Calcineurin Inhibitors processed this record on July 21, 2017