The Effects and Cost-Effectiveness of an Integrated Multidisciplinary Approach for Psychogeriatric Patients

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00402311
Recruitment Status : Completed
First Posted : November 22, 2006
Last Update Posted : January 22, 2007
ZonMw: The Netherlands Organisation for Health Research and Development
Information provided by:
Maastricht University Medical Center

Brief Summary:
The purpose of this study is to determine the effects and cost-effectiveness of a Diagnostic Observation Center for PsychoGeriatric patients (DOC-PG). Our main hypothesis is that DOC-PG has added value compared with usual care regarding Health Related Quality of Life (HRQoL).

Condition or disease Intervention/treatment Phase
Delirium, Dementia, Amnestic, Cognitive Disorders Memory Disorders Procedure: DOC-PG: integrated multidisciplinary assessment Procedure: Usual care: assessment by GP or one of the regional services Not Applicable

Detailed Description:

An integrated multidisciplinary approach to diagnosing and managing dementia is generally recommended, though rarely investigated. In recent years, multidisciplinary memory clinics (MCs) for patients with dementia have been established in many places over the world. These services have recently also been criticised for being principally hospital-based, for their apparently limited focus that entails only medical diagnostics and pharmacotherapy and for thus diverting resources from community mental health teams(CMHTs) .On the other hand, CMHTs are mainly concerned with the provision and organisation of integrated care, and unlike MCs, CMHTs generally have limited access to hospital-based diagnostics such as brain-imaging.

In April 2002, an outpatient diagnostic facility, the Diagnostic Observation Centre for PsychoGeriatric patients (DOC-PG) was established in Maastricht, the Netherlands. DOC-PG combines the hospital-based approach of the MC with the care-oriented approach of the regional CMHT and aims to provide the general practitioner (GP) with elaborate diagnostic and therapeutic advice for patients with cognitive disorders.

Comparison: DOC-PG is compared with usual care i.e. the GP took care of the diagnosis, or he or she referred the patient to one of the separate regional services, e.g. the Maastricht Memory Clinic (MMC), geriatric medicine, or the department of mental health for the elderly of the mental health community service (CMHT).

Study Type : Interventional  (Clinical Trial)
Enrollment : 216 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Diagnostic
Official Title: A Prospective Randomized Trial on the Effects of a Psychogeriatric Diagnostic Day Hospital
Study Start Date : April 2002
Study Completion Date : August 2005

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Memory

Primary Outcome Measures :
  1. The Visual Analogue Scale of the EuroQol-5D

Secondary Outcome Measures :
  1. Utility score of the EuroQol-5D
  2. Short Form 36 (SF-36)
  3. Mini Mental State Examination (MMSE)
  4. Global Deterioration Scale (GDS)
  5. NeuroPsychiatric Inventory (NPI)
  6. Instrumental Activities of Daily Living scale (IADL)
  7. Cornell Scale of Depression in Dementia (CSDD)
  8. Perceived Pressure from Informal Care (Dutch translation, EDIZ)
  9. Informal care questionnaire

Information from the National Library of Medicine

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Ages Eligible for Study:   55 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Aged 55 years or over
  • Suspected of having dementia or combined somatic/psychiatric disorder
  • No referral to other local/regional services in the last two years
  • Availability of a proxy (visiting the patient at least once a week)

Exclusion Criteria:

  • Acute disorders that need a prompt therapeutic intervention
  • Living in a nursing home or receiving care that is comparable to that of a nursing home

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00402311

Academic Hospital Maastricht
Maastricht, Limburg, Netherlands, 6202 AZ
Sponsors and Collaborators
Maastricht University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development
Principal Investigator: Frans R Verhey, PhD, MD Maastricht University Medical Center
Study Director: Carmen D. Dirksen, PhD Maastricht University Medical Center
Study Director: Johan L Severens, PhD Maastricht University Medical Center
Study Chair: Alfons Kessels, MD, MSc Maastricht University Medical Center
Study Chair: Claire A Wolfs, MSc Maastricht University Medical Center

Additional Information:
Publications of Results:
Other Publications:
Wolfs CAG, Severens JL, Dirksen CD, Kessels A, Jaspers N, Verhey FRJ. 2005. A Randomized Clinical Trial on the Effects of a Diagnostic Observation Centre for PsychoGeriatric patients (DOC-PG). International Psychogeriatrics 17: 370-371

Publications automatically indexed to this study by Identifier (NCT Number): Identifier: NCT00402311     History of Changes
Other Study ID Numbers: 945-02-055
First Posted: November 22, 2006    Key Record Dates
Last Update Posted: January 22, 2007
Last Verified: November 2006

Keywords provided by Maastricht University Medical Center:
Health Services for the Aged
Geriatric Psychiatry

Additional relevant MeSH terms:
Cognition Disorders
Memory Disorders
Neurocognitive Disorders
Pathologic Processes
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Mental Disorders
Neurobehavioral Manifestations
Neurologic Manifestations
Signs and Symptoms