Maintenance Effect of Clobex Shampoo on Subjects With Moderate to Severe Scalp Psoriasis
|Scalp Psoriasis||Drug: Clobex Shampoo 0.05% Drug: clobex shampoo placebo||Phase 3|
|Study Design:||Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
|Official Title:||Comparison of the Maintenance Effect of Clobex® Shampoo 0.05% Used Twice Weekly vs. Vehicle on Scalp Psoriasis in Subjects Who Successfully Responded to a 4-Week Daily Course of Clobex® Shampoo 0.05%|
- Global severity score [ Time Frame: 1st relapse ]
- Safety [ Time Frame: all visits ]
- Quality of Life [ Time Frame: end of study phases ]
|Study Start Date:||September 2006|
|Study Completion Date:||August 2007|
Drug: Clobex Shampoo 0.05%
|Placebo Comparator: 2||
Drug: clobex shampoo placebo
Psoriasis is a chronic disease that affects the skin, the scalp and joints. Scalp psoriasis is very common and can have an important impact on people's life.
Primary objective of scalp psoriasis treatments is to gain initial and rapid control of the disease process with a minimum of side-effects and improve patient quality of life.
Still, one of the unmet needs of scalp psoriasis therapies is the maintenance of a long-term remission. For corticosteroids in particular, one of the drawbacks is the disease recurrences after cessation of the treatment.
Therefore the establishment of a modified corticosteroid dosing regimen that would allow remission with minimal side-effects is suitable.
The purpose of this study is to assess how long a patient can be successfully maintained in a good condition when using Clobex® shampoo only twice a week.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00400725
|centre de Recherche Dermatologique du Québec|
|Principal Investigator:||Poulin, MD||Centre de Recherche Dermatologique du Quebec Métropolitain|