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DAHANCA 20 Palliative Radiotherapy for Head and Neck Cancer

This study has been completed.
Danish Head and Neck Cancer Group
Information provided by (Responsible Party):
Kenneth Jensen, University of Aarhus Identifier:
First received: November 15, 2006
Last updated: June 18, 2013
Last verified: June 2013
Palliative radiotherapy for head and neck cancer is widely used but the effect and side effects are largely unknown. We will study the effect of short hypofractionated palliative radiotherapy (20 Gy in 4 fractions) on symptom intensity and -frequency as weel as side effects

Condition Intervention Phase
Head and Neck Neoplasms
Neoplasms, Second Primary
Procedure: Radiotherapy
Phase 2

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: DAHANCA 20 Palliative Radiotherapy for Head and Neck Cancer

Resource links provided by NLM:

Further study details as provided by University of Aarhus:

Primary Outcome Measures:
  • Frequency and intensity of symptoms before and after radiotherapy (EORTC C30 and H&N35 questionnaires and CTC AE 3.0 toxicity scores) [ Time Frame: 11 mths ]

Secondary Outcome Measures:
  • Survival [ Time Frame: 11 mths ]
  • Side effects [ Time Frame: 2 mths ]
  • Other treatments [ Time Frame: 11 mths ]

Estimated Enrollment: 100
Study Start Date: November 2006
Study Completion Date: June 2012
Primary Completion Date: June 2012 (Final data collection date for primary outcome measure)
Intervention Details:
    Procedure: Radiotherapy
    20 Gy in 4 fx

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Incurable primary or second primary head and neck cancer
  • Speaks and reads Danish
  • Capable of filling out questionnaires for at leas two months after radiotherapy
  • Age>=18 years
  • Expected survival> 3months
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Please refer to this study by its identifier: NCT00400426

Department of Oncology
Aarhus, Denmark, 8000 C
Sponsors and Collaborators
University of Aarhus
Danish Head and Neck Cancer Group
Principal Investigator: Kenneth Jensen, MD DAHANCA (Danish Head and Neck Cancer Group)
  More Information

Additional Information:
Responsible Party: Kenneth Jensen, MD ph.d., University of Aarhus Identifier: NCT00400426     History of Changes
Other Study ID Numbers: DAHANCA 20
Study First Received: November 15, 2006
Last Updated: June 18, 2013

Keywords provided by University of Aarhus:
Palliative radiotherapy
Head and neck Neoplasm
Quality of life

Additional relevant MeSH terms:
Head and Neck Neoplasms
Neoplasms, Second Primary
Neoplasms by Site
Disease Attributes
Pathologic Processes processed this record on May 22, 2017