Effect of Repaglinide and Metformin Combination Tablet or Rosiglitazone and Metformin in Fixed Dose Combination on Blood Glucose Control in Patients With Type 2 Diabetes
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This trial is conducted in the United States of America (USA). This trial compares the changes in HbA1c after 26 weeks of repaglinide and metformin fixed dose combination tablet given as twice daily versus three times daily regimens or versus twice daily rosiglitazone and metformin fixed dose combination tablet in subjects with type 2 diabetes currently on monotherapy.
Condition or disease
DiabetesDiabetes Mellitus, Type 2
Drug: repaglinide and metformin combination tabletDrug: rosiglitazone and metformin combination tablet
Repaglinide and Metformin Combination Tablet (NN4440) in a TID Regimen Compared to a BID Regimen and BID Avandamet in Subjects With Type 2 Diabetes: A Twenty-Six Week, Open-Label, Multicenter, Randomized, Parallel Group Trial to Investigate Efficacy and Safety
Study Start Date
Primary Completion Date
Study Completion Date
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Ages Eligible for Study:
18 Years and older (Adult, Senior)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Type 2 diabetes for at least 3 months
HbA1c between 7.5-11.0% on monotherapy or
HbA1c between 7.0-10.0% on dual therapy
BMI maximum 45 kg/m2
Any clinically significant disease history in the opinion of the investigator