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Is it Possible to Treat Cyanide Poisoning With HBO?

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified November 2006 by Rigshospitalet, Denmark.
Recruitment status was:  Recruiting
Sponsor:
ClinicalTrials.gov Identifier:
NCT00399100
First Posted: November 14, 2006
Last Update Posted: November 14, 2006
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
Rigshospitalet, Denmark
  Purpose

People who has been in a fire accident have been shown often to be cyanide poisoned as well as poisoned with carbon monoxide(CO). According to recommendations from the Danish Health Agency people who are CO poisoned must be treated with hyperbaric oxygen (HBO). We want to see if HBO treatment can also treat cyanide poisoning.

The hypothesis is that as cyanide binds the same place in the mitochondria as CO cyanide will be detached from the mitochondria like CO and diffuse back to the blood.This way it will be easier to treat with hydroxycobalamin.


Condition Intervention
Carbon Monoxide Poisoning From Fire Accidents Procedure: HBO - hyperbaric oxygen treatment

Study Type: Observational
Study Design: Observational Model: Defined Population
Time Perspective: Longitudinal
Time Perspective: Prospective

Resource links provided by NLM:


Further study details as provided by Rigshospitalet, Denmark:

Study Start Date: November 2006
Estimated Study Completion Date: November 2006
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Criteria

Inclusion Criteria:

  • Going to receive HBO treatment for carbon monoxide poisoning from fire accidents

Exclusion Criteria:

  • Under 18 years
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00399100


Contacts
Contact: Pia Lawson-Smith, Doctor 0045 3545 9455 Lawson_Smith@dadlnet.dk
Contact: Ole Hyldegaard Larsen, Doctor 0045 3545 8859

Locations
Denmark
Lab. for hyperbar medicin, afs. 4092, Anæstesi og Operationsklinikken, HOC, Rigshospitalet Recruiting
København Ø, Denmark, 2100
Sponsors and Collaborators
Rigshospitalet, Denmark
Investigators
Principal Investigator: Pia Lawson-Smith, Doctor Rigshospitalet HOC, Trykkammeret
  More Information

ClinicalTrials.gov Identifier: NCT00399100     History of Changes
Other Study ID Numbers: 01-277/99
First Submitted: November 13, 2006
First Posted: November 14, 2006
Last Update Posted: November 14, 2006
Last Verified: November 2006

Additional relevant MeSH terms:
Poisoning
Carbon Monoxide Poisoning
Chemically-Induced Disorders
Gas Poisoning