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Is it Possible to Treat Cyanide Poisoning With HBO?

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ClinicalTrials.gov Identifier: NCT00399100
Recruitment Status : Unknown
Verified November 2006 by Rigshospitalet, Denmark.
Recruitment status was:  Recruiting
First Posted : November 14, 2006
Last Update Posted : November 14, 2006
Information provided by:
Rigshospitalet, Denmark

Brief Summary:

People who has been in a fire accident have been shown often to be cyanide poisoned as well as poisoned with carbon monoxide(CO). According to recommendations from the Danish Health Agency people who are CO poisoned must be treated with hyperbaric oxygen (HBO). We want to see if HBO treatment can also treat cyanide poisoning.

The hypothesis is that as cyanide binds the same place in the mitochondria as CO cyanide will be detached from the mitochondria like CO and diffuse back to the blood.This way it will be easier to treat with hydroxycobalamin.

Condition or disease Intervention/treatment
Carbon Monoxide Poisoning From Fire Accidents Procedure: HBO - hyperbaric oxygen treatment

Study Type : Observational
Observational Model: Defined Population
Time Perspective: Longitudinal
Time Perspective: Prospective
Study Start Date : November 2006
Estimated Study Completion Date : November 2006

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Poisoning
U.S. FDA Resources

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All

Inclusion Criteria:

  • Going to receive HBO treatment for carbon monoxide poisoning from fire accidents

Exclusion Criteria:

  • Under 18 years

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00399100

Contact: Pia Lawson-Smith, Doctor 0045 3545 9455 Lawson_Smith@dadlnet.dk
Contact: Ole Hyldegaard Larsen, Doctor 0045 3545 8859

Lab. for hyperbar medicin, afs. 4092, Anæstesi og Operationsklinikken, HOC, Rigshospitalet Recruiting
København Ø, Denmark, 2100
Sponsors and Collaborators
Rigshospitalet, Denmark
Principal Investigator: Pia Lawson-Smith, Doctor Rigshospitalet HOC, Trykkammeret

ClinicalTrials.gov Identifier: NCT00399100     History of Changes
Other Study ID Numbers: 01-277/99
First Posted: November 14, 2006    Key Record Dates
Last Update Posted: November 14, 2006
Last Verified: November 2006

Additional relevant MeSH terms:
Carbon Monoxide Poisoning
Chemically-Induced Disorders
Gas Poisoning