Is it Possible to Treat Cyanide Poisoning With HBO?

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00399100
Recruitment Status : Completed
First Posted : November 14, 2006
Last Update Posted : March 21, 2018
Information provided by:
Rigshospitalet, Denmark

Brief Summary:

People who has been in a fire accident have been shown often to be cyanide poisoned as well as poisoned with carbon monoxide(CO). According to recommendations from the Danish Health Agency people who are CO poisoned must be treated with hyperbaric oxygen (HBO). We want to see if HBO treatment can also treat cyanide poisoning.

The hypothesis is that as cyanide binds the same place in the mitochondria as CO cyanide will be detached from the mitochondria like CO and diffuse back to the blood.This way it will be easier to treat with hydroxycobalamin.

Condition or disease Intervention/treatment
Carbon Monoxide Poisoning From Fire Accidents Procedure: HBO - hyperbaric oxygen treatment

Study Type : Observational
Enrollment : 20 participants
Observational Model: Case-Control
Time Perspective: Prospective
Actual Study Start Date : November 2006
Actual Primary Completion Date : November 2006
Actual Study Completion Date : November 2006

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Poisoning

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All

Inclusion Criteria:

  • Going to receive HBO treatment for carbon monoxide poisoning from fire accidents

Exclusion Criteria:

  • Under 18 years

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00399100

Lab. for hyperbar medicin, afs. 4092, Anæstesi og Operationsklinikken, HOC, Rigshospitalet
København Ø, Denmark, 2100
Sponsors and Collaborators
Rigshospitalet, Denmark
Principal Investigator: Pia Lawson-Smith, Doctor Rigshospitalet HOC, Trykkammeret Identifier: NCT00399100     History of Changes
Other Study ID Numbers: 01-277/99
First Posted: November 14, 2006    Key Record Dates
Last Update Posted: March 21, 2018
Last Verified: November 2006

Additional relevant MeSH terms:
Carbon Monoxide Poisoning
Chemically-Induced Disorders
Gas Poisoning