A Non-invasive Approach to the Assessment of Volume Status in Mechanically Ventilated Septic Patients.

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00398736
Recruitment Status : Completed
First Posted : November 14, 2006
Last Update Posted : July 15, 2009
Information provided by:
Charite University, Berlin, Germany

Brief Summary:

To evaluate the use of sonographic inferior caval vein assessment in mechanically ventilated septic patients.

Volume assessment in mechanically ventilated patients with inflammation is of major importance to guide fluid therapy. The researchers investigated whether measurement of caval vein diameter correlates with invasively assessed volume-based hemodynamic parameters.

Condition or disease Intervention/treatment
Severe Sepsis Septic Shock Procedure: sonographic measurement of inferior caval vein diameter

Study Type : Observational
Observational Model: Case-Only
Time Perspective: Prospective

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MedlinePlus related topics: Sepsis Shock

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 90 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Sampling Method:   Probability Sample
Study Population
Critically ill patients with sepsis

Inclusion Criteria:

  • age 18-90
  • presence of severe sepsis and septic shock
  • invasive hemodynamic monitoring using the picco system

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00398736

Sponsors and Collaborators
Charite University, Berlin, Germany
Principal Investigator: Joerg C Dr. Schefold, MD Charite University Medicine Identifier: NCT00398736     History of Changes
Other Study ID Numbers: Caval vein sonography
First Posted: November 14, 2006    Key Record Dates
Last Update Posted: July 15, 2009
Last Verified: July 2009

Keywords provided by Charite University, Berlin, Germany:
Presence of severe sepsis and septic shock, mechanical ventilation

Additional relevant MeSH terms:
Shock, Septic
Systemic Inflammatory Response Syndrome
Pathologic Processes