This site became the new on June 19th. Learn more.
Show more Menu IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu IMPORTANT: Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu
Give us feedback

A Non-invasive Approach to the Assessment of Volume Status in Mechanically Ventilated Septic Patients.

This study has been completed.
Information provided by:
Charite University, Berlin, Germany Identifier:
First received: November 13, 2006
Last updated: July 14, 2009
Last verified: July 2009

To evaluate the use of sonographic inferior caval vein assessment in mechanically ventilated septic patients.

Volume assessment in mechanically ventilated patients with inflammation is of major importance to guide fluid therapy. The researchers investigated whether measurement of caval vein diameter correlates with invasively assessed volume-based hemodynamic parameters.

Condition Intervention Phase
Severe Sepsis Septic Shock Procedure: sonographic measurement of inferior caval vein diameter Phase 2

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective

Resource links provided by NLM:

Further study details as provided by Charite University, Berlin, Germany:


Ages Eligible for Study:   18 Years to 90 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Sampling Method:   Probability Sample
Study Population
Critically ill patients with sepsis

Inclusion Criteria:

  • age 18-90
  • presence of severe sepsis and septic shock
  • invasive hemodynamic monitoring using the picco system
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00398736

Sponsors and Collaborators
Charite University, Berlin, Germany
Principal Investigator: Joerg C Dr. Schefold, MD Charite University Medicine
  More Information Identifier: NCT00398736     History of Changes
Other Study ID Numbers: Caval vein sonography
Study First Received: November 13, 2006
Last Updated: July 14, 2009

Keywords provided by Charite University, Berlin, Germany:
Presence of severe sepsis and septic shock, mechanical ventilation

Additional relevant MeSH terms:
Shock, Septic
Systemic Inflammatory Response Syndrome
Pathologic Processes
Shock processed this record on September 21, 2017