A Non-invasive Approach to the Assessment of Volume Status in Mechanically Ventilated Septic Patients.

This study has been completed.
Information provided by:
Charite University, Berlin, Germany
ClinicalTrials.gov Identifier:
First received: November 13, 2006
Last updated: July 14, 2009
Last verified: July 2009

To evaluate the use of sonographic inferior caval vein assessment in mechanically ventilated septic patients.

Volume assessment in mechanically ventilated patients with inflammation is of major importance to guide fluid therapy. The researchers investigated whether measurement of caval vein diameter correlates with invasively assessed volume-based hemodynamic parameters.

Condition Intervention Phase
Severe Sepsis
Septic Shock
Procedure: sonographic measurement of inferior caval vein diameter
Phase 2

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective

Resource links provided by NLM:

Further study details as provided by Charite University, Berlin, Germany:


Ages Eligible for Study:   18 Years to 90 Years
Genders Eligible for Study:   Both
Sampling Method:   Probability Sample
Study Population
Critically ill patients with sepsis

Inclusion Criteria:

  • age 18-90
  • presence of severe sepsis and septic shock
  • invasive hemodynamic monitoring using the picco system
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00398736

Sponsors and Collaborators
Charite University, Berlin, Germany
Principal Investigator: Joerg C Dr. Schefold, MD Charite University Medicine
  More Information

ClinicalTrials.gov Identifier: NCT00398736     History of Changes
Other Study ID Numbers: Caval vein sonography 
Study First Received: November 13, 2006
Last Updated: July 14, 2009
Health Authority: Germany: Federal Institute for Drugs and Medical Devices

Keywords provided by Charite University, Berlin, Germany:
Presence of severe sepsis and septic shock, mechanical ventilation

Additional relevant MeSH terms:
Shock, Septic
Pathologic Processes
Systemic Inflammatory Response Syndrome

ClinicalTrials.gov processed this record on May 26, 2016