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Clinical and Pathologic Studies in Non-Hodgkin's Lymphoma Patients Receiving Antibody Treatment

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT00398372
Recruitment Status : Completed
First Posted : November 10, 2006
Last Update Posted : June 2, 2011
Sponsor:
Collaborators:
Amgen
National Institutes of Health (NIH)
Information provided by:
Stanford University

Study Description
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Brief Summary:
To characterize the molecular and cell biology of the tumor cells in lymphoma. The mechanism of monoclonal antibody treatment by rituximab or epratuzumab will also be examined.

Condition or disease Intervention/treatment Phase
Lymphoma, Non-Hodgkin Lymphomas: Non-Hodgkin Lymphomas: Non-Hodgkin Cutaneous Lymphoma Lymphomas: Non-Hodgkin Diffuse Large B-Cell Lymphomas: Non-Hodgkin Follicular / Indolent B-Cell Lymphomas: Non-Hodgkin Mantle Cell Lymphomas: Non-Hodgkin Marginal Zone Lymphomas: Non-Hodgkin Peripheral T-Cell Lymphomas: Non-Hodgkin Waldenstr Macroglobulinemia Drug: Rituximab Drug: Epratuzumab Not Applicable

Study Design
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Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 500 participants
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Official Title: Le20: Clinical and Pathologic Studies in Non-Hodgkin's Lymphoma Patients Receiving Antibody Treatment
Study Start Date : November 2000
Actual Primary Completion Date : June 2007
Actual Study Completion Date : September 2009

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Lymphoma

Arms and Interventions
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Outcome Measures
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Primary Outcome Measures :
  1. To characterize the molecular and cell biology of the tumor cells in lymphoma. [ Time Frame: 6 months ]

Eligibility Criteria
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Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria
Inclusion Criteria:Non-Hodgkin's Lymphoma Patients Receiving Antibody Treatment
Contacts and Locations
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Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00398372


Locations
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United States, California
Stanford University School of Medicine
Stanford, California, United States, 94305
Sponsors and Collaborators
Stanford University
Amgen
National Institutes of Health (NIH)
Investigators
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Principal Investigator: Wen-Kai Weng Stanford University
More Information
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Responsible Party: Wen-Kai Weng, Stanford University School of Medicine
ClinicalTrials.gov Identifier: NCT00398372    
Other Study ID Numbers: LYMNHL0031
200114861
77550
CA09287
CA111827
LYMNHL0031
First Posted: November 10, 2006    Key Record Dates
Last Update Posted: June 2, 2011
Last Verified: July 2010
Additional relevant MeSH terms:
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Lymphoma
Lymphoma, Non-Hodgkin
Lymphoma, T-Cell, Cutaneous
Neoplasms by Histologic Type
Neoplasms
Lymphoproliferative Disorders
Lymphatic Diseases
Immunoproliferative Disorders
Immune System Diseases
 Lymphoma, T-Cell
Rituximab
Epratuzumab
Antineoplastic Agents, Immunological
Antineoplastic Agents
Immunologic Factors
Physiological Effects of Drugs
Antirheumatic Agents