Hydrogen Sulfide Production by Oral Microflora

This study has been completed.
Information provided by:
Hadassah Medical Organization
ClinicalTrials.gov Identifier:
First received: November 6, 2006
Last updated: February 1, 2009
Last verified: November 2006
Oral malodor is a common condition. In most cases this condition results from the proteolytic activity of anaerobic oral bacteria. These bacteria produce volatile sulfide compounds which are fowl smelling and are felt during exhalation and speech. the aim of the present study is to examine a simple method of detecting these bacteria in samples taken from the oral cavity of oral malodor patients.

Oral Malodor (Halitosis)

Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: Detection of Hydrogen Sulfide Production by Oral Microflora Samples

Further study details as provided by Hadassah Medical Organization:

Estimated Enrollment: 60
Study Start Date: January 2007
Study Completion Date: September 2008
Primary Completion Date: August 2008 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   18 Years to 45 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • oral malodor patients

Exclusion Criteria:

  • smokers, users of antibiotic one month prior to study
  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00396539

Hadassah Medical Organization
Jerusalem, Israel
Sponsors and Collaborators
Hadassah Medical Organization
Principal Investigator: Nir Sterer, Dr. Hadassah Medical Organization
  More Information

ClinicalTrials.gov Identifier: NCT00396539     History of Changes
Other Study ID Numbers: 29.12.06-19-HMO-CTIL 
Study First Received: November 6, 2006
Last Updated: February 1, 2009
Health Authority: Israel: Israeli Health Ministry Pharmaceutical Administration

Additional relevant MeSH terms:
Hydrogen Sulfide
Molecular Mechanisms of Pharmacological Action
Neurotransmitter Agents
Pharmacologic Actions
Physiological Effects of Drugs

ClinicalTrials.gov processed this record on May 05, 2016