We updated the design of this site on December 18, 2017. Learn more.
ClinicalTrials.gov Menu

Hydrogen Sulfide Production by Oral Microflora

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT00396539
Recruitment Status : Completed
First Posted : November 7, 2006
Last Update Posted : February 3, 2009
Information provided by:
Hadassah Medical Organization

Brief Summary:
Oral malodor is a common condition. In most cases this condition results from the proteolytic activity of anaerobic oral bacteria. These bacteria produce volatile sulfide compounds which are fowl smelling and are felt during exhalation and speech. the aim of the present study is to examine a simple method of detecting these bacteria in samples taken from the oral cavity of oral malodor patients.

Condition or disease
Oral Malodor (Halitosis)

Study Type : Observational
Estimated Enrollment : 60 participants
Time Perspective: Prospective
Official Title: Detection of Hydrogen Sulfide Production by Oral Microflora Samples
Study Start Date : January 2007
Primary Completion Date : August 2008
Study Completion Date : September 2008

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Ages Eligible for Study:   18 Years to 45 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • oral malodor patients

Exclusion Criteria:

  • smokers, users of antibiotic one month prior to study

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00396539

Hadassah Medical Organization
Jerusalem, Israel
Sponsors and Collaborators
Hadassah Medical Organization
Principal Investigator: Nir Sterer, Dr. Hadassah Medical Organization

ClinicalTrials.gov Identifier: NCT00396539     History of Changes
Other Study ID Numbers: 29.12.06-19-HMO-CTIL
First Posted: November 7, 2006    Key Record Dates
Last Update Posted: February 3, 2009
Last Verified: November 2006

Additional relevant MeSH terms:
Signs and Symptoms, Digestive
Signs and Symptoms
Hydrogen Sulfide
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action
Physiological Effects of Drugs