This site became the new on June 19th. Learn more.
Show more Menu IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu IMPORTANT: Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu
Give us feedback

Efficacy of Lifestyle Changes in Modifying Practical Markers of Wellness and Aging.

This study has been completed.
Information provided by:
St. Anthony's Health Care Identifier:
First received: November 1, 2006
Last updated: NA
Last verified: November 2006
History: No changes posted
To assess the impact of lifestylel changes upon measures of wellness and aging, in particular weight change, fitness measures, and cognitive performance. The hypothesis was that aerobic exercise would improve mental performance and measures of fitness.

Condition Intervention
Aging Behavioral: Aerobic exercise

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Prevention
Official Title: Efficacy of Lifestyle Changes in Modifying Practical Markers of Wellness and Aging

Further study details as provided by St. Anthony's Health Care:

Primary Outcome Measures:
  • Cognitive performance (memory, psychomotor speed, reaction time, attention, cognitive flexibility)

Secondary Outcome Measures:
  • Cholesterol profile
  • Weight change
  • Body fat change
  • Changes in fitness (strength, flexibility, VO2max)

Estimated Enrollment: 56
Study Start Date: September 2004
Estimated Study Completion Date: May 2006
Detailed Description:

A 10-week, randomized control study conducted in a wellness center in St. Petersburg, Florida. Adults age 21-65, exercising less than 3 days/week. 56 subjects were randomized to a control or an intervention group. Subjects followed a diet with >30 grams of fiber and <16 grams of saturated fat daily, and were taught to reach 70-85% of their maximum heart rate 5-6 days/week, and to perform strength training 3 days/week, plus were asked to participate in 10-20 minutes of stress management activities daily. The study was designed to determine body composition, maximal aerobic capacity (VO2 max), total cholesterol/high-density lipoprotein (TC/HDL), and cognition.

Specific aspects ofcognitive performance were noted to increase with increasing levels of aerobic activity, but not with strength training, dietary fiber change, or stress managment.

Having established that the treatment group would exercise at different levels of intensity, additional subjects were recruited, and the cognitive performance of no exercise, moderate aerobic exercise, and frequent aerobic exercise could be compared with specific domains of cognitive performance: memory, psychomotor speed, reaction time, attention, and cognitive flexibility. The St Anthony’s Institutional Review Board approved this research project.


Ages Eligible for Study:   18 Years to 70 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • able to exercise 5-6 days per week

Exclusion Criteria:

  • Free of major medical conditions, unable to exercise aerobically 5-6 days per week
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00395837

United States, Florida
Carillon Wellness Center
St Petersburg, Florida, United States, 33716
Sponsors and Collaborators
St. Anthony's Health Care
Principal Investigator: Steven C Masley Medical Director
  More Information Identifier: NCT00395837     History of Changes
Other Study ID Numbers: #S2004.004
Study First Received: November 1, 2006
Last Updated: November 1, 2006

Keywords provided by St. Anthony's Health Care:
Aerobic exercise
Prevention processed this record on September 21, 2017