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Airways Dysfunction Following WTC Dust Exposure

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ClinicalTrials.gov Identifier: NCT00395330
Recruitment Status : Completed
First Posted : November 2, 2006
Last Update Posted : August 20, 2015
Sponsor:
Information provided by:
New York University School of Medicine

Study Description
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Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information
Brief Summary:
In the weeks following the terrorist attacks of September 11, 2001, many patients presented to their physicians with complaints related to exposure to the debris. These included nose and throat complaints (drip, congestion, sore throat), increased GE reflux (heartburn, regurgitation, retrosternal chest burning) and respiratory symptoms (worsening cough, wheezing, shortness of breath, chest tightness, sleep disturbance). In addition, there was a disproportionate rate of self-reported worsening asthma symptoms in patients living in Lower New York 5-9 weeks after the attack; those with exposure to the dust cloud fared worse. The functional abnormalities of firefighters with exposures to dust at the WTC site has been recently described. However, the effects of WTC dust exposure on pulmonary function in residents and workers near the WTC site remain unclear. This study will retrospectively review the charts of all patients referred to the pulmonary function laboratory for evaluation of symptoms following exposure to WTC dust. The main objectives for this study will be to characterize the functional abnormalities in these subjects.

Condition or disease
Pulmonary Diseases

Study Design
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Study Type : Observational
Enrollment : 500 participants
Observational Model: Ecologic or Community
Time Perspective: Retrospective
Official Title: Airways Dysfunction Following WTC Dust Exposure
Study Start Date : April 2003
Actual Primary Completion Date : October 2006
Actual Study Completion Date : October 2006
Groups and Cohorts
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Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information


Outcome Measures
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Eligibility Criteria
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Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
study will retrospectively review the charts of all patients referred to the pulmonary function laboratory for evaluation of symptoms following exposure to WTC dust.
Criteria

Inclusion Criteria:

  • age 18-80
  • referral for pulmonary function evaluation of respiratory symptoms following exposure to WTC dust

Exclusion Criteria:

  • inability to perform testing
Contacts and Locations
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Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00395330


Sponsors and Collaborators
New York University School of Medicine
Investigators
Principal Investigator: Kenneth I Berger, MD New York University School of Medicine
More Information
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Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):

ClinicalTrials.gov Identifier: NCT00395330     History of Changes
Other Study ID Numbers: H06-714
First Posted: November 2, 2006    Key Record Dates
Last Update Posted: August 20, 2015
Last Verified: August 2015

Keywords provided by New York University School of Medicine:
Respiratory Function Tests
Oscillometry
World Trade Center Disaster
Environmental Exposure
Distal Airways

Additional relevant MeSH terms:
Lung Diseases
Respiratory Tract Diseases