Inflammation in Children With Attention-Deficit/Hyperactivity Disorder (ADHD_CYTO)
Recruitment status was: Not yet recruiting
|Study Design:||Observational Model: Case Control
Time Perspective: Cross-Sectional
Time Perspective: Prospective
|Official Title:||Inflammation in Children With Attention-Deficit/Hyperactivity Disorder|
|Study Start Date:||September 2007|
|Estimated Study Completion Date:||December 2007|
Attention deficit-hyperactivity disorder (ADHD) is a prevalent childhood neuropsychiatric disorder, characterized by age-inappropriate and impairing levels of inattention, hyperactivity and impulsiveness. Approximately 5-10% of school-age children are affected by ADHD, and in many cases, symptoms persist into adolescence and adulthood.
Cytokines are key mediators of immune function and can be either pro-inflammatory or anti-inflammatory. Recently few studies have suggested involvement of cytokine pathways in subjects with ADHD.
Polymorphism of IL-1 receptors antagonists' alleles have been suggested in families and subjects suffering from ADHD. Moreover, a new variant of inflammatory bowel disease, another immunological based disease, was recently suggested in children with ADHD and other developmental disorders. There are no other published reports on cytokine production in children who suffer from ADHD.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00391495
|The Unit of Clinical Nutrition|
|Tel Aviv, Israel|
|Principal Investigator:||Nachum Vaisman, Prof. (MD)||Tel-Aviv Sourasky Medical Center|