Bioelectric Field Imaging in Diagnosing Melanoma and Other Skin Cancers in Patients With Skin Lesions

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00391300
Recruitment Status : Unknown
Verified October 2008 by National Cancer Institute (NCI).
Recruitment status was:  Active, not recruiting
First Posted : October 23, 2006
Last Update Posted : December 18, 2013
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
Information provided by:
National Cancer Institute (NCI)

Brief Summary:

RATIONALE: New diagnostic procedures, such as bioelectric field imaging, may help find and diagnose melanoma and other skin cancers. It may also be a less invasive way to check for skin cancer.

PURPOSE: This phase I trial is studying bioelectric field imaging in diagnosing melanoma and other skin cancers in patients with skin lesions.

Condition or disease Intervention/treatment Phase
Melanoma (Skin) Non-melanomatous Skin Cancer Procedure: bioelectric field imaging Procedure: biopsy Procedure: histopathologic examination Phase 1

Detailed Description:


  • To determine if the hand-held Bioelectric Field Imager can be used to measure the electric field in skin of various body surfaces, including face, neck, shoulders, arms, hands, chest, back, legs, and feet, during the course of examination and treatment of patients with suspected malignant skin lesions.
  • To determine if there is a significant difference between the lateral electric field strength near benign and malignant skin lesions in the same individual.

OUTLINE: Patients undergo scanning of their skin lesions and nearby healthy skin using the Bioelectric Field Imager (BFI). The lesions are then biopsied for histological diagnosis. Histological data from the biopsy is correlated with the electric field data from the BFI.

Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 100 participants
Primary Purpose: Diagnostic
Official Title: Development of an Electrical Diagnostic for Melanoma and Other Cutaneous Malignancies
Study Start Date : October 2006
Estimated Primary Completion Date : April 2007
Estimated Study Completion Date : April 2007

Resource links provided by the National Library of Medicine

Primary Outcome Measures :
  1. Use of Bioelectric Field Imager (BFI) in measuring the electric field in skin of various body surfaces
  2. Use of BFI in detecting significant electric field differences between malignant and benign skin lesions

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No


  • Suspected malignant skin lesion
  • Seeking treatment for skin lesion at the VA Medical Center


  • Not pregnant
  • No acute illness, including upper respiratory tract infection or flu that could result in fever
  • No trauma to the skin lesion area
  • No prisoners


  • See Disease Characteristics

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00391300

United States, Virginia
VA Hospital
Hampton, Virginia, United States, 23667
Sponsors and Collaborators
Eastern Virginia Medical School
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
Principal Investigator: Antoinette F. Hood, MD Eastern Virginia Medical School Identifier: NCT00391300     History of Changes
Other Study ID Numbers: CDR0000616117
EVMS-BFI and Lesions
First Posted: October 23, 2006    Key Record Dates
Last Update Posted: December 18, 2013
Last Verified: October 2008

Keywords provided by National Cancer Institute (NCI):
basal cell carcinoma of the skin
squamous cell carcinoma of the skin

Additional relevant MeSH terms:
Skin Neoplasms
Neuroendocrine Tumors
Neuroectodermal Tumors
Neoplasms, Germ Cell and Embryonal
Neoplasms by Histologic Type
Neoplasms, Nerve Tissue
Nevi and Melanomas
Neoplasms by Site
Skin Diseases