Effect of Rofecoxib and a Narcotic Analgesic to Treat Pain Following Arthroscopic Surgery (0966-179)(COMPLETED)
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Ages Eligible for Study:
18 Years to 60 Years (Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Elective outpatient arthroscopic knee surgery expected to last <= 90 minutes using general anesthesia
Patients must experience moderate to severe pain following surgery
Patient must be in general good health as judged by the primary investigator
Osteoarthritis; rheumatoid arthritis
Allergy/sensitivity to aspirin, ibuprofen, indomethacin, other NSAIDs, COX-2 inhibitors (e.g., rofecoxib, celecoxib), hydrocodone, acetaminophen
Asthma associated with nasal polyps
Any arthroscopic knee surgery in the past 6 months