Evaluation of Consultation Including Genetic Aspects of Obesity
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00389246|
Recruitment Status : Completed
First Posted : October 18, 2006
Last Update Posted : October 2, 2017
|Condition or disease||Intervention/treatment||Phase|
|Obesity||Behavioral: Consultation without genetic information Behavioral: Consultation with genetic information||Phase 3|
More than 1,000 obese people are screened for genetic mutations (MC4R). Those with positive screenings as well as 320 randomly selected people without MC4R mutations are randomized to 2 consultation types: one including recommendations for eating and physical activity behavior, the other with an additional part on genetic determinants and actions in obesity. Their results are compared to a control group (n>100). It is hypothesized that obese people with obesity-specific genetic mutations, and obese people with a family history of obesity, benefit more if the consultation includes additional elements on genetic determinants.
The following variables are used: BMI, SCID interview for mental disorders, Stunkard's body silhouttes for participants and their parents and siblings, Restraint Eating Scale, PANAS, Well-being scale, body acceptance, shame and guilt, coping with obesity, participant's satisfaction with consultation.
Assessment Points: before consultation, after consultation, 6 months later.
|Study Type :||Interventional (Clinical Trial)|
|Enrollment :||420 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||Evaluation of Consultation Including Genetic Aspects of Obesity|
|Study Start Date :||September 2002|
|Study Completion Date :||June 2005|
- Feeling guilty for being overweight
- Negative affectivity
- body acceptance
- restraint eating
- qualityof life
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00389246
|Principal Investigator:||Winfried Rief, PhD||Philipps University of Marburg, Marburg, Germany|