Strength Training Effectiveness Post-Stroke (STEPS)
|Cerebrovascular Accident||Procedure: exercise therapy Procedure: walking rehabilitation||Phase 2|
|Study Design:||Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Single Blind (masked role unspecified)
Primary Purpose: Treatment
|Official Title:||Strength Training Effectiveness Post-Stroke (STEPS)|
- walking speed (meters/second)
- walking distance (distance walked in 6-minutes)
- Lower extremity Fugl-Meyer
- Berg Balance Score
- Lower extremity torque
- Stroke Impact Scale
|Study Start Date:||May 2004|
|Study Completion Date:||October 31, 2010|
|Primary Completion Date:||October 31, 2010 (Final data collection date for primary outcome measure)|
Impaired walking ability is a hallmark residual deficit that contributes to post-stroke walking disability . Impairment in lower extremity muscle strength is a significant contributor to decreased walking speed after stroke. No studies have combined task-specific locomotor training in combination with lower extremity strength training programs designed to improve post-stroke walking outcomes.
Participants will include individuals who are ambulatory, but walk slower than 1.0 m/sec and are at least 6 months post unilateral stroke.
Participants are stratified by initial comfortable walking speed (moderate >0.5 m/sec; severe <= 0.5 m/sec) and randomized to one of four exercise pairs: 1) body-weight supported treadmill training (BWST) and locomotor-based strength training (resistive cycling task, LBST), 2) BWST and LE muscle-specific strength training (MSST), 3) BWST and upper extremity ergometry (SHAM), and 4) LBST and SHAM. Training will occur 4 times per week for 6 weeks (24 total sessions). Exercise type in each exercise pair is alternated daily.
Primary outcomes include comfortable and fast overground walking speed, and distance walked in 6-minutes measured at baseline, after 12 and 24 treatment sessions and at a 6-month follow-up.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00389012
|United States, California|
|Rancho Los Amigos|
|Downey, California, United States, 90242|
|University of Southern California|
|Los Angeles, California, United States, 90089|
|United States, Illinois|
|Chicago, Illinois, United States, 60611|
|Principal Investigator:||Katherine J Sullivan, PhD, PT||Division of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, California|
|Principal Investigator:||David A Brown, PhD, PT||Department of Physical Therapy and Movement Sciences, Feinberg School of Medicine, Northwestern University, Chicago, Illinois|
|Principal Investigator:||Sara Mulroy, PhD, PT||Pathokinesiology Laboratory, Rancho Los Amigos National Rehabilitation Center, Downey, California|