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Renal Artery Calcium and Hypertension

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ClinicalTrials.gov Identifier: NCT00388869
Recruitment Status : Unknown
Verified October 2006 by Hadassah Medical Organization.
Recruitment status was:  Not yet recruiting
First Posted : October 17, 2006
Last Update Posted : October 17, 2006
Sponsor:
Information provided by:
Hadassah Medical Organization

Brief Summary:

CT of the abdomen is a very common examination performed for various indications.One of the common findings is vascular calcifications including calcifications of the renal arteries.Calcifications in the carotid arteries and coronary arteries are good predictor for obstructive atherosclerotic disease.Stenosis of the renal arteries can cause symptomatic or asymptomatic hypertension with subsequent clinical sequelae. Therefore early diagnosis of this condition is imperative.

The goal of our study is to investigate the correlation between incidental calcifications of the renal arteries in CT examinations and the presence of actual stenosis of these vessels in patients with and without hypertension.


Condition or disease
Hypertension Atherosclerosis

Detailed Description:

Every patient aged 30-100 referred for abdominal CT examination with IV contrast injection will be included in this study (total 300 patients.Prior to the examination relevant clinical data including history of hypertension and predisposing conditions for atherosclerotic disease, will be investigated. The patient will undergo conventional CT with no special procedures. The images will be review by the radiologist for the presence of renal arteries calcifications, renal arteries stenosis,plaque location, plaque burden and characterization and secondary renal pathology.

This study will not change the examination technique and is not associated with any inconvenience to the patients.


Study Type : Observational
Estimated Enrollment : 300 participants
Observational Model: Defined Population
Primary Purpose: Screening
Time Perspective: Longitudinal
Time Perspective: Prospective
Official Title: Calcifications of the Renal Arteries and Renal Artery Stenosis in Patients With and Without Hypertension?
Study Start Date : November 2006




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Ages Eligible for Study:   30 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Every patient referred fo abdominal CT aged 30-100

Exclusion Criteria:

  • Contraindication for IV contrast injection failure to demonstrate renal arteries with contrast refusal to sign an informed consent

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00388869


Contacts
Contact: Nurith Hiller, MD 972-50-7874980 hiller@netvision.net.il

Locations
Israel
Hadassah Medical Organization Not yet recruiting
Jerusalem, Israel
Contact: Arik Tzukert, DMD    00-972-2-6776095    arik@hadassah.org.il   
Contact: Hadas Lemberg, phD    00-972-2-6777572    lhadas@hadassah.org.il   
Principal Investigator: Nurith Hiller, MD         
Sponsors and Collaborators
Hadassah Medical Organization
Investigators
Principal Investigator: Nurith Hiller, MD Hadassah Medical Organization

ClinicalTrials.gov Identifier: NCT00388869     History of Changes
Other Study ID Numbers: HILLER-HMO-CTIL
First Posted: October 17, 2006    Key Record Dates
Last Update Posted: October 17, 2006
Last Verified: October 2006

Keywords provided by Hadassah Medical Organization:
renal artery
calcium
CT
hypertension

Additional relevant MeSH terms:
Hypertension
Atherosclerosis
Vascular Diseases
Cardiovascular Diseases
Arteriosclerosis
Arterial Occlusive Diseases