Safety and Effectiveness of Cardiac Resynchronization Therapy With Defibrillation
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Device: Cardiac Resynchronization Therapy with Defibrillation
Phase 2Phase 3
Patients enrolled received a device with cardiac resynchronization therapy (CRT) and defibrillation. Patients were randomized to CRT on or off for up to six months and evaluated for mortality, hospitalization, and functional outcomes including exercise capacity, quality of life, symptomatic status, and echocardiographic analysis.
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Layout table for eligibility information
Ages Eligible for Study:
Child, Adult, Older Adult
Sexes Eligible for Study:
Symptomatic heart failure
Left ventricular ejection fraction <= 35%
QRS width >= 120 ms
Indicated for an implantable cardioverter defibrillator