Exercise Study For People With Parkinson's Disease
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|ClinicalTrials.gov Identifier: NCT00387218|
Recruitment Status : Unknown
Verified May 2008 by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).
Recruitment status was: Recruiting
First Posted : October 12, 2006
Last Update Posted : May 23, 2008
|Condition or disease||Intervention/treatment||Phase|
|Parkinson's Disease||Behavioral: Exercise, Physical therapy||Not Applicable|
This is an intervention study that will determine whether an exercise program targeting spinal extremity range of motion for individuals with Parkinson's Disease, is superior to general conditioning and to 'usual care'. This study builds on previous findings of Schenkman and colleagues including the following: loss of spinal and extremity range of motion occur as sequelae to PD; these losses contribute significantly to early impairments of balance; and both spinal range of motion and balance of people with economy of movement is impaired in people who have PD. Specifically, we will examine whether the intervention, targeting range of motion and balance, also improves economy of movement.
Untreated impairments of range of motion, balance, and economy of movement may become highly disabling. Short term improvements of range of motion and balance occur with exercise. If the patient can sustain such improvements after a supervised exercise program is completed, these functionally limiting impairments may be delayed. Additionally, if exercises for spinal range of motion are coupled with functional retraining, the patient should improve in overall physical functional ability. Therefore, this study will establish the overall impact of a targeted exercise program for people with PD in terms of balance, economy of movement, and overall functional ability.
The study is a randomized clinical trial, with three treatment arms and four repeated measures: before treatment, after treatment, and follow-up after 10 months and again after 16 months. This study compares usual care based on the National Parkinson's Foundation, aerobic training, and targeted flexibility and functional training. The primary outcomes are measures of overall functional ability, balance and economy of movement. Secondary outcomes include measures of disease state, spinal range of motion, aerobic capacity, and quality of life.
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||170 participants|
|Intervention Model:||Single Group Assignment|
|Official Title:||Exercise, Physical Function, and Parkinson's Disease|
|Study Start Date :||December 2002|
|Estimated Primary Completion Date :||April 2009|
|Estimated Study Completion Date :||April 2009|
- Balance (Functional Reach)
- Economy of movement (Oxygen consumption)
- Functional capacity (Continuous Scale Physical Functional Performance Test (Cs-PFP)
- UPDRS Motor subscale
- UPDRS ADL subscale
- Quality of life (PDQ-39)
- Spinal Range of Motion (Functional Axial Rotation, FAR)
- VO2 submax
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00387218
|Contact: Cory L Christiansen, PT, PhDfirstname.lastname@example.org|
|United States, Colorado|
|Waldron's Peak Physical Therapy||Recruiting|
|Boulder, Colorado, United States, 80303|
|Colorado Springs, Colorado, United States, 80933|
|University of Colorado at Denver and Health Sciences Center||Recruiting|
|Denver, Colorado, United States, 80262|
|Carmody Recreation Center||Recruiting|
|Lakewood, Colorado, United States, 80227|
|Principal Investigator:||Margaret L Schenkman, PhD, PT||University of Colorado, Denver|