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Somatosensory Processing in Depression

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ClinicalTrials.gov Identifier: NCT00386893
Recruitment Status : Withdrawn
First Posted : October 12, 2006
Last Update Posted : April 14, 2015
Sponsor:
Collaborator:
H. Lundbeck A/S
Information provided by (Responsible Party):
Oliver Pogarell, Ludwig-Maximilians - University of Munich

Brief Summary:
Aim of this study is to investigate neuronal differences (EEG/evoked potentials; functional MRI) between patients with major depression and healthy controls concerning brain activity after acute pain as well as changes of pain related brain activity during treatment with escitalopram.

Condition or disease Intervention/treatment Phase
Depression Procedure: simultaneous EEG/fMRI Device: fMRI Phase 4

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 0 participants
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Diagnostic
Official Title: Influence of Escitalopram on Somatosensory Processing in Patients With Major Depression
Study Start Date : October 2006
Actual Primary Completion Date : December 2011
Actual Study Completion Date : December 2011

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Arm Intervention/treatment
Treatment as usual
simultaneous EEG/fMRI
Procedure: simultaneous EEG/fMRI
fMRI/EEG recordings
Device: fMRI



Primary Outcome Measures :
  1. changes in evoked potentials/functional MRI from baseline to week 4 [ Time Frame: two assessments, at baseline and week 4 ]


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Ages Eligible for Study:   18 Years to 60 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Psychiatric in or outpatients with acute depressive episode
  • Indication for pharmacological treatment

Exclusion Criteria:

  • Acute suicidal tendency
  • Neurological or severe somatic disorders
  • Women during pregnancy or lactation

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00386893


Locations
Germany
Department of Psychiatry and Clin. Radiology, Ludwig-Maximilian-University
Munich, Bavaria, Germany, D - 80336
Sponsors and Collaborators
Ludwig-Maximilians - University of Munich
H. Lundbeck A/S
Investigators
Principal Investigator: Ulrich Hegerl, MD Department of Psychiatry, Ludwig-Maximilians-University
Principal Investigator: Oliver Pogarell, MD Department of Psychiatry, Ludwig-Maximilians-University

Responsible Party: Oliver Pogarell, Investigator, Ludwig-Maximilians - University of Munich
ClinicalTrials.gov Identifier: NCT00386893     History of Changes
Other Study ID Numbers: ESC_03082005
2005-003752-35
First Posted: October 12, 2006    Key Record Dates
Last Update Posted: April 14, 2015
Last Verified: April 2015

Additional relevant MeSH terms:
Depression
Depressive Disorder
Behavioral Symptoms
Mood Disorders
Mental Disorders