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Somatosensory Processing in Depression

This study has been withdrawn prior to enrollment.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00386893
First Posted: October 12, 2006
Last Update Posted: April 14, 2015
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Collaborator:
H. Lundbeck A/S
Information provided by (Responsible Party):
Oliver Pogarell, Ludwig-Maximilians - University of Munich
  Purpose
Aim of this study is to investigate neuronal differences (EEG/evoked potentials; functional MRI) between patients with major depression and healthy controls concerning brain activity after acute pain as well as changes of pain related brain activity during treatment with escitalopram.

Condition Intervention Phase
Depression Procedure: simultaneous EEG/fMRI Device: fMRI Phase 4

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Diagnostic
Official Title: Influence of Escitalopram on Somatosensory Processing in Patients With Major Depression

Further study details as provided by Oliver Pogarell, Ludwig-Maximilians - University of Munich:

Primary Outcome Measures:
  • changes in evoked potentials/functional MRI from baseline to week 4 [ Time Frame: two assessments, at baseline and week 4 ]

Enrollment: 0
Study Start Date: October 2006
Study Completion Date: December 2011
Primary Completion Date: December 2011 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Treatment as usual
simultaneous EEG/fMRI
Procedure: simultaneous EEG/fMRI
fMRI/EEG recordings
Device: fMRI

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 60 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Psychiatric in or outpatients with acute depressive episode
  • Indication for pharmacological treatment

Exclusion Criteria:

  • Acute suicidal tendency
  • Neurological or severe somatic disorders
  • Women during pregnancy or lactation
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00386893


Locations
Germany
Department of Psychiatry and Clin. Radiology, Ludwig-Maximilian-University
Munich, Bavaria, Germany, D - 80336
Sponsors and Collaborators
Ludwig-Maximilians - University of Munich
H. Lundbeck A/S
Investigators
Principal Investigator: Ulrich Hegerl, MD Department of Psychiatry, Ludwig-Maximilians-University
Principal Investigator: Oliver Pogarell, MD Department of Psychiatry, Ludwig-Maximilians-University
  More Information

Responsible Party: Oliver Pogarell, Investigator, Ludwig-Maximilians - University of Munich
ClinicalTrials.gov Identifier: NCT00386893     History of Changes
Other Study ID Numbers: ESC_03082005
2005-003752-35
First Submitted: October 10, 2006
First Posted: October 12, 2006
Last Update Posted: April 14, 2015
Last Verified: April 2015

Additional relevant MeSH terms:
Depression
Depressive Disorder
Behavioral Symptoms
Mood Disorders
Mental Disorders