Metabolic Study of Concentric and Eccentric Muscle Training
|Lipid Metabolism Insulin Resistance Inflammation||Behavioral: physical training|
|Study Design:||Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)
Primary Purpose: Educational/Counseling/Training
- Metabolic and anti-inflammatory effects induced by eccentric muscle exercise.
- Metabolic and anti-inflammatory effects induced by concentric muscle exercise.
|Study Start Date:||April 2003|
|Estimated Study Completion Date:||August 2003|
Physical exercise decreases the risk of obesity, diabetes mellitus, and cardiovascular disease. Skeletal muscle can be exercised by two ways: Concentric contraction is defined as active shortening of muscles, e.g. by stepping upwards, whereas eccentric muscle contraction is defined as active resistance to stretching, e.g. by stepping downwards. Although the effects of exercise (i.e. the combination of concentric and eccentric muscle contraction) on metabolic parameters have been extensively investigated, there are no data on the specific metabolic effects of concentric versus those of eccentric muscle work in humans.
Comparison(s): Metabolic and anti-inflammatory effects of eccentric endurance exercise (i.e. stepping upwards), compared to metabolic and anti-inflammatory effects of concentric exercise (i.e. stepping downwards).
Please refer to this study by its ClinicalTrials.gov identifier: NCT00386854
|Vorarlberg Institute of Vascular Investigation and Treatment|
|Feldkirch, Vorarlberg, Austria, 6807|
|Principal Investigator:||Heinz Drexel, MD||Vorarlberg Institut of Vascular Investigation and Treatment, Academic Teaching Hospital, Austria|