Metabolic Study of Concentric and Eccentric Muscle Training
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|ClinicalTrials.gov Identifier: NCT00386854|
Recruitment Status : Completed
First Posted : October 12, 2006
Last Update Posted : October 12, 2006
|Condition or disease||Intervention/treatment||Phase|
|Lipid Metabolism Insulin Resistance Inflammation||Behavioral: physical training||Not Applicable|
Physical exercise decreases the risk of obesity, diabetes mellitus, and cardiovascular disease. Skeletal muscle can be exercised by two ways: Concentric contraction is defined as active shortening of muscles, e.g. by stepping upwards, whereas eccentric muscle contraction is defined as active resistance to stretching, e.g. by stepping downwards. Although the effects of exercise (i.e. the combination of concentric and eccentric muscle contraction) on metabolic parameters have been extensively investigated, there are no data on the specific metabolic effects of concentric versus those of eccentric muscle work in humans.
Comparison(s): Metabolic and anti-inflammatory effects of eccentric endurance exercise (i.e. stepping upwards), compared to metabolic and anti-inflammatory effects of concentric exercise (i.e. stepping downwards).
|Study Type :||Interventional (Clinical Trial)|
|Enrollment :||40 participants|
|Intervention Model:||Crossover Assignment|
|Masking:||None (Open Label)|
|Study Start Date :||April 2003|
|Study Completion Date :||August 2003|
- Metabolic and anti-inflammatory effects induced by eccentric muscle exercise.
- Metabolic and anti-inflammatory effects induced by concentric muscle exercise.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00386854
|Vorarlberg Institute of Vascular Investigation and Treatment|
|Feldkirch, Vorarlberg, Austria, 6807|
|Principal Investigator:||Heinz Drexel, MD||Vorarlberg Institut of Vascular Investigation and Treatment, Academic Teaching Hospital, Austria|