Referral Recommendations for Axial Spondyloarthritis
|Official Title:||Performance of Referral Recommendations in Patients With Chronic Back Pain and Suspected Axial Spondyloarthritis|
|Study Start Date:||July 2004|
|Primary Completion Date:||April 2007 (Final data collection date for primary outcome measure)|
Ankylosing spondylitis (AS) and its early form accounts for up to 5% of all patients with chronic back pain. Shortening the delay of 5-10 years between first symptoms and making a diagnosis of AS has become a challenge especially because effective treatments have become available. Easy to apply referral parameters for physicians in primary care may contribute to make the diagnosis earlier.
Methods: Orthopedists and primary care physicians were offered to refer patients with i) chronic low back pain (duration >3 months) and ii) onset of back pain at an age < 45 years to a specialized rheumatology outpatient clinic for further diagnostic work-up if at least one of the following screening parameters was present: 1) inflammatory back pain (IBP), 2) positive HLA-B27, 3) sacroiliitis as detected by imaging. The final diagnosis was made according to expert opinion.
It was analyzed, which parameters or combination of parameters performed best in making a diagnosis of axial SpA.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00383617
|Department of Rheumatology, Medical Clinic I, Charite Campus Benjamin Franklin, Hindenburgdamm 30|
|Berlin, Germany, 12200|
|Principal Investigator:||Joachim Sieper, MD||Department of Rheumatology, Medical Clinic I, Charité University Medicine Berlin, Campus Benjamin Franklin, Berlin, Germany|