Emergency Pharmacist Safety Study

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00382434
Recruitment Status : Completed
First Posted : September 29, 2006
Last Update Posted : January 14, 2010
Agency for Healthcare Research and Quality (AHRQ)
Information provided by:
University of Rochester

Brief Summary:
The Emergency Department (ED) is a unique environment in medicine, and many safety mechanisms used in other hospital settings cannot be applied in the ED. For example, clinical pharmacists have traditionally provided extra layers of protection to hospital inpatients by cross-checking provider orders for appropriate dosing, contraindications, and interactions. Because medications in the ED must be accessed immediately and are often one-time doses, the use of central pharmacy services would introduce an unacceptable delay to the administration of medication. Although some hospitals have programs in place in which a pharmacist responds to the ED for cardiac arrests or trauma team activations, few have reported programs which involve a clinical pharmacist assigned exclusively to the emergency department. Nonetheless, published reports have asserted that ED-based pharmacists can increase patient safety. Although this concept appears logical, no study has attempted to show that these programs reduce potential adverse drug events in the ED. We propose to implement and optimize an ED Pharmacist (EDP) program as a safe practice intervention in a large ED. The hospital has provided funding for two permanent full time positions starting at the beginning of the award period. In the initial phase interviews of physicians, nurses, pharmacists, and patients will be conducted and the results will be used to optimize the EDP role. A large-scale chart review study will then be conducted to evaluate whether there is a reduction in frequency of potential and adverse drug events during times that the EDP is on duty. Staff perceptions of the effectiveness of this program will also be evaluated. The overall goal of this initiative is to create an effective EDP program that will decrease the rate of adverse drug events in ED patients, and to create a "toolkit" to facilitate the introduction of similar programs into other EDs. This toolkit will include a description of the formal, optimized role of the EDP, challenges and solutions in implementation, and evidence to support the efficacy of such a program.

Condition or disease Intervention/treatment
Adverse Drug Event, Potential Adverse Drug Event, and Quality Measures Procedure: presence of an emergency pharmacist in the ED

Study Type : Observational
Actual Enrollment : 10224 participants
Time Perspective: Prospective
Official Title: The ED Pharmacist as a Safety Measure in Emergency Medicine
Study Start Date : August 2005
Actual Study Completion Date : December 2006

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Drug Reactions

Group/Cohort Intervention/treatment
EPh Present
the emergency pharmacist is present in the ED when the medical care is provided
Procedure: presence of an emergency pharmacist in the ED

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Sampling Method:   Probability Sample
Study Population
emergency department patients

Inclusion Criteria:

  • pediatric (less than 19), geriatric (>64), or critically ill (all ages)

Exclusion Criteria:

  • investigator involved or incomplete chart

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00382434

United States, New York
University of Rochester Medical Center
Rochester, New York, United States, 14642
Sponsors and Collaborators
University of Rochester
Agency for Healthcare Research and Quality (AHRQ)
Principal Investigator: Rollin J Fairbanks, MD, MS University of Rochester

Additional Information: Identifier: NCT00382434     History of Changes
Other Study ID Numbers: 1U18HS015818 ( U.S. AHRQ Grant/Contract )
RSRB #11834
First Posted: September 29, 2006    Key Record Dates
Last Update Posted: January 14, 2010
Last Verified: January 2010

Keywords provided by University of Rochester:
emergency pharmacist
emergency medicine
emergency department
medical error
adverse event
patient safety

Additional relevant MeSH terms:
Drug-Related Side Effects and Adverse Reactions
Disease Attributes
Pathologic Processes
Chemically-Induced Disorders