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Study Evaluation LXR-623 in Healthy Adults

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ClinicalTrials.gov Identifier: NCT00379860
Recruitment Status : Terminated
First Posted : September 25, 2006
Last Update Posted : March 9, 2007
Sponsor:
Information provided by:
Wyeth is now a wholly owned subsidiary of Pfizer

Brief Summary:
To evaluate the safety and tolerability of multiple doses of LXR in healthy adults.

Condition or disease Intervention/treatment Phase
Healthy Subjects Drug: LXR-623 Phase 1

Study Type : Interventional  (Clinical Trial)
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Double
Primary Purpose: Treatment
Official Title: A Multiple Ascending Dose Study of the Safety, Pharmacokinetics, and Pharmacodynamics of LXR-623 Administered Orally to Healthy Subjects
Study Start Date : October 2006
Study Completion Date : January 2007



Primary Outcome Measures :
  1. Safety is the primary outcome.


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Ages Eligible for Study:   18 Years to 50 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Generally healthy adults.
  • Liver function tests, triglycerideres, and creatinine must be below upper limit of normal at screening.

Exclusion Criteria:

  • A history or active presence of clinically important medical disease.
  • Any metal implants or devices.
  • Claustrophobia.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00379860


Sponsors and Collaborators
Wyeth is now a wholly owned subsidiary of Pfizer
Investigators
Study Director: Medical Monitor Wyeth is now a wholly owned subsidiary of Pfizer

ClinicalTrials.gov Identifier: NCT00379860     History of Changes
Other Study ID Numbers: 3201A1-101
First Posted: September 25, 2006    Key Record Dates
Last Update Posted: March 9, 2007
Last Verified: March 2007