Tranexamic Acid vs. Quixil - Reducing Blood Loss in Joint Replacement
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|ClinicalTrials.gov Identifier: NCT00378872|
Recruitment Status : Completed
First Posted : September 21, 2006
Last Update Posted : May 14, 2008
|Condition or disease||Intervention/treatment||Phase|
|Hemorrhage Arthroplasty, Replacement, Hip Arthroplasty, Replacement, Knee||Drug: IV Tranexamic acid 10mg/kg pt body weight Drug: Quixil topical sealant||Not Applicable|
This is a prospective randomised controlled trial to compare the benefits of Quixil vs. Tranexamic acid in reducing blood loss.
Both medicines are used for the reduction of blood loss in major joint surgery; previous studies have shown each one to be effective and safe, but they have not been directly compared in this setting.
We will compare the blood loss in each of 3 groups: tranexamic acid used, Quixil used, and control group (neither drug used). Blood loss is to be calculated from height, body weight and difference between pre and post-operation haematocrit.
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||132 participants|
|Intervention Model:||Parallel Assignment|
|Official Title:||Prospective Randomised Trial Comparing Intraoperative Topical Quixil and Intravenous Tranexamic Acid, in Reduction of Blood Loss Following Primary Hip & Knee Joint Replacement Surgery.|
|Study Start Date :||June 2006|
|Actual Primary Completion Date :||May 2008|
|Actual Study Completion Date :||May 2008|
- Blood loss as calculated from change in haematocrit
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00378872
|Golden Jubilee National Hospital|
|Clydebank, Scotland, United Kingdom, G81 4HX|
|Principal Investigator:||Jamie S McConnell, MB BCh MRCS||Golden Jubilee National Hospital, NHS Scotland|