Barrier Function and Production of Inflammatory Cytokines in the Rectal Mucosa in Patients With Septic Shock
Recruitment status was: Not yet recruiting
Life-threatening infection impairs bloodflow to the gut, thereby causing less delivery of oxygen. This leads to increased formation of different inflammatory and infectious markers.
The investigators hypothesize, therefore, that there is a significant difference in the concentrations of inflammatory and infectious markers in the rectal mucosa between patients with septic shock and healthy controls.
Procedure: Rectal biopsy
Procedure: Measurement of inflammatory markers in the rectal mucosa
Procedure: Measurement of rectal lactic acid
|Study Design:||Time Perspective: Prospective|
|Official Title:||Barrier Function and Production of Inflammatory Cytokines in the Rectal Mucosa in Patients With Septic Shock|
Please refer to this study by its ClinicalTrials.gov identifier: NCT00378586
|Dept. of Intensive Care 4131|
|Copenhagen, Denmark, DK-2100|
|Principal Investigator:||Michael Ibsen, MD||Dept. of Intensive Care 4131, Rigshospitalet, Copenhagen, Denmark|