Lifetime Risk for Cardiovascular Disease Among Non-White Ethnic Groups

This study has been completed.
Information provided by:
National Heart, Lung, and Blood Institute (NHLBI) Identifier:
First received: September 14, 2006
Last updated: December 13, 2007
Last verified: December 2007
Cardiovascular disease (CVD) is one of the leading causes of death in the United States. Currently, there is little information about the lifetime risk of CVD among non-white ethnic groups. This study will analyze data from participants in several ongoing clinical studies to identify the lifetime risk for CVD among various ethnicities.

Cardiovascular Diseases
Coronary Disease
Heart Failure, Congestive
Atrial Fibrillation

Study Type: Observational
Study Design: Time Perspective: Retrospective
Official Title: Epidemiologic Study of Ethnicity and Lifetime Risks for Cardiovascular Disease

Resource links provided by NLM:

Further study details as provided by National Heart, Lung, and Blood Institute (NHLBI):

Estimated Enrollment: 500000
Study Start Date: July 2006
Estimated Study Completion Date: July 2006
Detailed Description:

CVD affects millions of people in the United States. Current treatment guidelines for CVD take into account an individual's risk of developing the disease within 10 years; the intensity of therapy is usually matched to the 10-year risk magnitude. However, many individuals have a low 10-year risk of CVD, but have an elevated lifetime risk of developing the disease. Unfortunately, few studies have examined the lifetime risks for CVD, and these studies have been almost exclusively performed in the Caucasian population. There have been no studies that focus on the lifetime risks for CVD among other ethnic groups. Because the incidence of CVD and other causes of death vary among different ethnic groups, it is important to examine each group separately. Using data from ongoing clinical studies, this study will evaluate the lifetime risks for CVD among different ethnic groups. The results from this study will assist in estimating the future incidence of CVD among ethnic groups, improving risk communication within patient care, and identifying new populations of individuals at risk for CVD.

This study will use previously collected data on 500,000 individuals participating in pre-specified clinical studies. Some of the participating studies include the following: Atherosclerosis Risk in Communities, Framingham Heart, Honolulu Heart, Puerto Rico Heart Health, Coronary Artery Risk Development in Young Adults (CARDIA), Cardiovascular Health, Chicago Heart Association Detection Project in Industry, Women's Health Initiative Observational Studies, and Multiple Risk Factor Intervention Trial (MRFIT). There will be no study visits specifically for this study. Researchers will collect information on CVD risk factors and demographics, including sex, race, and age; they will then compare this information to overall survival, CVD associated survival, and lifetime risk for CVD.


Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Participating in a specified epidemiologic study

Exclusion Criteria:

  • Pre-existing CVD prior to study entry
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00377702

United States, Illinois
Northwestern University Department of Preventive Medicine
Chicago, Illinois, United States, 60611
Sponsors and Collaborators
National Heart, Lung, and Blood Institute (NHLBI)
Principal Investigator: Donald M. Lloyd-Jones, MD, ScM Northwestern University
  More Information

No publications provided Identifier: NCT00377702     History of Changes
Other Study ID Numbers: 1350, R21 HL085375
Study First Received: September 14, 2006
Last Updated: December 13, 2007
Health Authority: United States: Federal Government

Keywords provided by National Heart, Lung, and Blood Institute (NHLBI):
Coronary Heart Disease
Risk Factors
Heart Failure

Additional relevant MeSH terms:
Atrial Fibrillation
Cardiovascular Diseases
Coronary Artery Disease
Coronary Disease
Heart Failure
Arrhythmias, Cardiac
Arterial Occlusive Diseases
Heart Diseases
Myocardial Ischemia
Pathologic Processes
Vascular Diseases processed this record on November 27, 2015