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A Comparison of Manual vs. Spontaneous Removal of the Placenta at Cesarean Section

This study has been completed.
Information provided by:
University of Rochester Identifier:
First received: September 11, 2006
Last updated: November 12, 2007
Last verified: November 2007
The purpose of this study is to determine if there are differences in operative blood loss with manual vs. spontaneous removal of the placenta during cesarean section.

Condition Intervention
Cesarean Section
Procedure: Manual placental removal at Cesarean delivery
Procedure: Spontaneous placental removal at Cesarean delivery

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Open Label
Official Title: A Comparison of Manual vs. Spontaneous Removal of the Placenta at Cesarean Section

Resource links provided by NLM:

Further study details as provided by University of Rochester:

Primary Outcome Measures:
  • Hematocrit levels (preoperatively and within 48 hours postoperatively)

Secondary Outcome Measures:
  • Number of units of blood transfused intraoperatively and postoperatively
  • Development of uterine infection (endometritis)
  • Length of postoperative hospital stay
  • Operative time

Estimated Enrollment: 150
Study Start Date: September 2006
Study Completion Date: June 2007
Detailed Description:
Patients undergoing scheduled cesarean deliveries are randomized to manual or spontaneous placental removal.

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • All term pregnant women 18 years of age and older undergoing scheduled cesarean delivery at Strong Memorial Hospital.

Exclusion Criteria:

  • Prematurity (<37 weeks)
  • Preoperative chorioamnionitis
  • Vaginal delivery of fetus
  • Emergency Cesarean Delivery
  • Patient's OB not agreeable to participating in this study.
  Contacts and Locations
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Please refer to this study by its identifier: NCT00375986

United States, New York
Strong Memorial Hospital
Rochester, New York, United States, 14642
Sponsors and Collaborators
University of Rochester
Principal Investigator: Eva K. Pressman, MD University of Rochester
  More Information Identifier: NCT00375986     History of Changes
Other Study ID Numbers: 00014248
Study First Received: September 11, 2006
Last Updated: November 12, 2007

Keywords provided by University of Rochester:
Cesarean delivery
Placental removal
Blood loss processed this record on May 25, 2017