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Study of Effectiveness of Hand Exercises to Treat Symptoms of Hand Osteoarthritis

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00375947
First Posted: September 13, 2006
Last Update Posted: August 23, 2007
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
The Arthritis Research Institute of America
  Purpose
Participants in this study will do hand exercises once per day for 16 weeks. The purpose of the study is to determine if hand exercises designed to improve range of movement and strength are an effective way to decrease functional limitations for people with hand osteoarthritis. The study will also attempt to determine if pain and stiffness are improved, and if hand strength and dexterity are improved.

Condition Intervention
Osteoarthritis Other: Hand Exercise Other: sham hand cream

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single
Primary Purpose: Treatment
Official Title: Efficacy of a Home-Based Hand Range-of-Motion and Strength Training Exercise Program for Improvement of Hand Function in Older Adults With Hand Osteoarthritis: a Randomized Controlled Trial

Resource links provided by NLM:


Further study details as provided by The Arthritis Research Institute of America:

Primary Outcome Measures:
  • Australian-Canadian Osteoarthritis Index (AUSCAN)hand disability score at 16 weeks of exercise

Secondary Outcome Measures:
  • AUSCAN hand pain score at 16 weeks of exercise
  • AUSCAN hand stiffness score at 16 weeks of exercise
  • Maximal and average grip strength at 16 weeks of exercise
  • Maximal and average key pinch strength at 16 weeks of exercise
  • Maximal and average 3-point pinch strength at 16 weeks of exercise
  • Purdue Peg Board dexterity scores at 16 weeks of exercise

Estimated Enrollment: 65
Study Start Date: November 2005
Study Completion Date: April 2007
Arms Assigned Interventions
Experimental: 1
Home-based hand exercise program
Other: Hand Exercise
Placebo Comparator: 2
Sham hand cream
Other: sham hand cream
placebo intervention

  Show Detailed Description

  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   50 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Men and women
  • Ages 50 years and older
  • Reside within Tampa Bay Region, Florida
  • Presence of symptomatic OA as determined by the AUSCAN Index. Specifically, a hand function score of > 225 mm for the AUSCAN VA-subscale
  • Presence of radiographic hand OA, as defined by grades 2, or higher, per the Kellgren and Lawrence scale in one or more joints.

Exclusion Criteria:

  • Concomitant rheumatic disease (e.g., rheumatoid arthritis, gout, lupus, fibromyalgia)
  • Current hand or wrist injury (e.g., carpal tunnel syndrome, palmer tenosynovitis, fracture, sprain)
  • Use of an assistive device such as a cane or crutch
  • Has hand surgery scheduled within the 48 weeks following the start of the study
  • Prior hand surgery requiring joint replacement or other instrumentation in the hands
  • Received any intra-articular injection (hyaluronic acid, corticosteroid, or joint lavage) during the 3 months preceding the study
  • Currently participating in another conflicting research study
  • Currently using a therapeutic hand cream or practicing a hand exercise routine
  • Unwilling to sign an informed consent
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00375947


Locations
United States, Florida
The Arthritis Research Institute of America
Clearwater, Florida, United States, 33755
Sponsors and Collaborators
The Arthritis Research Institute of America
Investigators
Principal Investigator: Matthew W Rogers, MS The Arthritis Research Institute of America
Study Director: Frances V Wilder, PhD The Arthritis Research Institute of America
  More Information

Additional Information:
ClinicalTrials.gov Identifier: NCT00375947     History of Changes
Other Study ID Numbers: ARIA-0001
First Submitted: September 11, 2006
First Posted: September 13, 2006
Last Update Posted: August 23, 2007
Last Verified: August 2007

Keywords provided by The Arthritis Research Institute of America:
exercise
hand disability
arthritis
AUSCAN

Additional relevant MeSH terms:
Osteoarthritis
Arthritis
Joint Diseases
Musculoskeletal Diseases
Rheumatic Diseases