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Non Alcoholic Fatty Liver Disease Influence of Statin Therapy

This study has been withdrawn prior to enrollment.
Sponsor:
Information provided by:
Shaare Zedek Medical Center
ClinicalTrials.gov Identifier:
NCT00375349
First received: September 11, 2006
Last updated: September 29, 2016
Last verified: September 2016
  Purpose

Aim:

  1. To determine the prevalence of fatty liver in a cohort of patients hospitalized with chest pain in the Cardiology department.
  2. To assess the effect of statins on the prevalence of fatty liver by a cross sectional survey of patients hospitalized with chest pain.

Condition Intervention
Non-alcoholic Fatty Liver Disease (NAFLD)
Procedure: Ultrasound to demonstrate existence of fatty liver

Study Type: Interventional

Resource links provided by NLM:


Further study details as provided by Shaare Zedek Medical Center:

Enrollment: 0
Study Start Date: September 2006
Estimated Study Completion Date: September 2009
Detailed Description:

Consecutive patients hospitalized with chest pain will be recruited at the cardiology department. Patients with an inflammatory condition, recent infection or history of alcoholism will be excluded. After signing an informed consent each patient will undergo an ultrasound examination for diagnosis of fatty liver. Information regarding BMI, hypertension and use of medications will be collected on each patient. Blood samples for fasting glucose, hemoglobin A1C, lipid profile, ESR, and CRP and liver function tests will be collected from each participant. Prevalence of fatty liver in patients who have been taking statins for 6 months or more statins will be compared to patients who have been taking statins for a lesser period and to those who do have not taken statins using a multivariate regression analysis.

Serum samples will be frozen and kept for future ongoing research.

  Eligibility

Ages Eligible for Study:   18 Years to 85 Years   (Adult, Senior)
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Cardiology patient
  • Age above 18

Exclusion Criteria:

  • Age below 18
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

No Contacts or Locations Provided
  More Information

Publications:
ClinicalTrials.gov Identifier: NCT00375349     History of Changes
Other Study ID Numbers: 20173CTIL 
Study First Received: September 11, 2006
Last Updated: September 29, 2016
Health Authority: Israel: Ethics Commission

Keywords provided by Shaare Zedek Medical Center:
fatty liver
statin
non-alcoholic

Additional relevant MeSH terms:
Liver Diseases
Fatty Liver
Non-alcoholic Fatty Liver Disease
Digestive System Diseases

ClinicalTrials.gov processed this record on December 07, 2016