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Non Alcoholic Fatty Liver Disease Influence of Statin Therapy

This study has been withdrawn prior to enrollment.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00375349
First Posted: September 12, 2006
Last Update Posted: September 30, 2016
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
Shaare Zedek Medical Center
  Purpose

Aim:

  1. To determine the prevalence of fatty liver in a cohort of patients hospitalized with chest pain in the Cardiology department.
  2. To assess the effect of statins on the prevalence of fatty liver by a cross sectional survey of patients hospitalized with chest pain.

Condition Intervention
Non-alcoholic Fatty Liver Disease (NAFLD) Procedure: Ultrasound to demonstrate existence of fatty liver

Study Type: Interventional

Resource links provided by NLM:


Further study details as provided by Shaare Zedek Medical Center:

Enrollment: 0
Study Start Date: September 2006
Estimated Study Completion Date: September 2009
Detailed Description:

Consecutive patients hospitalized with chest pain will be recruited at the cardiology department. Patients with an inflammatory condition, recent infection or history of alcoholism will be excluded. After signing an informed consent each patient will undergo an ultrasound examination for diagnosis of fatty liver. Information regarding BMI, hypertension and use of medications will be collected on each patient. Blood samples for fasting glucose, hemoglobin A1C, lipid profile, ESR, and CRP and liver function tests will be collected from each participant. Prevalence of fatty liver in patients who have been taking statins for 6 months or more statins will be compared to patients who have been taking statins for a lesser period and to those who do have not taken statins using a multivariate regression analysis.

Serum samples will be frozen and kept for future ongoing research.

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 85 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Cardiology patient
  • Age above 18

Exclusion Criteria:

  • Age below 18
  Contacts and Locations
No Contacts or Locations Provided
  More Information

Publications:
ClinicalTrials.gov Identifier: NCT00375349     History of Changes
Other Study ID Numbers: 20173CTIL
First Submitted: September 11, 2006
First Posted: September 12, 2006
Last Update Posted: September 30, 2016
Last Verified: September 2016

Keywords provided by Shaare Zedek Medical Center:
fatty liver
statin
non-alcoholic

Additional relevant MeSH terms:
Liver Diseases
Fatty Liver
Non-alcoholic Fatty Liver Disease
Digestive System Diseases