Preventing Depression Recurrence in Diabetes
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|ClinicalTrials.gov Identifier: NCT00374426|
Recruitment Status : Completed
First Posted : September 11, 2006
Last Update Posted : March 2, 2010
|Condition or disease||Intervention/treatment||Phase|
|Major Depression Diabetes||Drug: sertraline||Phase 4|
Part A: Prevention of Depression Recurrence in Diabetes
- To determine the efficacy of maintenance antidepressant medication in preventing or delaying recur-rence of major depression in diabetes.
- To determine the relationship of sustained depression remission to social, occupational, and global func-tioning, and to quality of life and compliance with diabetes treatment.
- To determine clinical features predictive of depression recurrence in diabetes.
Part B. Longitudinal Study of the Interrelationship of Glycemic Control and Depression
- To determine the effects of depression remission and recurrence on glycemic control.
- To determine the efficacy of maintenance antidepressant medication in producing sustained benefits in glycemic control.
- To determine the interrelationship of daily mood with blood glucose and the effect of maintenance treatment on this relationship.
|Study Type :||Interventional (Clinical Trial)|
|Enrollment :||262 participants|
|Intervention Model:||Parallel Assignment|
|Official Title:||Preventing Depression Recurrence in Diabetes|
|Study Start Date :||March 1998|
|Study Completion Date :||October 2004|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00374426
|United States, Missouri|
|Washington University School of Medicine|
|St. Louis, Missouri, United States, 63110|
|Principal Investigator:||Patrick J Lustman, Ph.D.||Washington University School of Medicine|