Triamcinolone Acetonide in Silicone-Filled Eyes as Adjunctive Treatment for Proliferative Vitreoretinopathy

This study has been completed.
Information provided by:
Shahid Beheshti Medical University Identifier:
First received: September 7, 2006
Last updated: October 11, 2006
Last verified: August 2006
To evaluate the effect of triamcinolone acetonide in silicone-filled eyes on the outcome of surgery for PVR.

Condition Intervention Phase
Proliferative Vitreoretinopathy
Drug: Triamcinolone acetonide
Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind
Primary Purpose: Treatment

Resource links provided by NLM:

Further study details as provided by Shahid Beheshti Medical University:

Primary Outcome Measures:
  • Single-operation retinal reattachment rate six
  • months after surgery.

Secondary Outcome Measures:
  • Visual acuity
  • Retinal reproliferation
  • Intraocular pressure
  • Early silicone oil emulsification

Study Start Date: June 2001
Estimated Study Completion Date: June 2003

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Cases of rhegmatogenous retinal detachment complicated by PVR grade C undergoing vitrectomy and silicone oil tamponade.

Exclusion Criteria:

  • History of trauma
  • Presence of diabetic retinopathy
  • History of vein occlusion
  • Giant retinal tear
  Contacts and Locations
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Please refer to this study by its identifier: NCT00373282

Iran, Islamic Republic of
Hamid Ahmadieh,MD
Tehran, Iran, Islamic Republic of, 16666
Sponsors and Collaborators
Shahid Beheshti Medical University
Principal Investigator: Hamid Ahmadieh, MD Ophthalmic Research Center of Shaheed Beheshti Medical University
  More Information

No publications provided Identifier: NCT00373282     History of Changes
Other Study ID Numbers: 8116
Study First Received: September 7, 2006
Last Updated: October 11, 2006
Health Authority: Iran: Ethics Committee

Keywords provided by Shahid Beheshti Medical University:
Retinal detachment
Silicone oil

Additional relevant MeSH terms:
Vitreoretinopathy, Proliferative
Eye Diseases
Retinal Diseases
Triamcinolone Acetonide
Triamcinolone diacetate
Triamcinolone hexacetonide
Anti-Inflammatory Agents
Enzyme Inhibitors
Hormones, Hormone Substitutes, and Hormone Antagonists
Immunologic Factors
Immunosuppressive Agents
Molecular Mechanisms of Pharmacological Action
Pharmacologic Actions
Physiological Effects of Drugs
Therapeutic Uses processed this record on November 27, 2015