Triamcinolone Acetonide in Silicone-Filled Eyes as Adjunctive Treatment for Proliferative Vitreoretinopathy

This study has been completed.
Information provided by:
Shahid Beheshti University of Medical Sciences Identifier:
First received: September 7, 2006
Last updated: October 11, 2006
Last verified: August 2006
To evaluate the effect of triamcinolone acetonide in silicone-filled eyes on the outcome of surgery for PVR.

Condition Intervention Phase
Proliferative Vitreoretinopathy
Drug: Triamcinolone acetonide
Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind
Primary Purpose: Treatment

Resource links provided by NLM:

Further study details as provided by Shahid Beheshti University of Medical Sciences:

Primary Outcome Measures:
  • Single-operation retinal reattachment rate six
  • months after surgery.

Secondary Outcome Measures:
  • Visual acuity
  • Retinal reproliferation
  • Intraocular pressure
  • Early silicone oil emulsification

Study Start Date: June 2001
Estimated Study Completion Date: June 2003

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Cases of rhegmatogenous retinal detachment complicated by PVR grade C undergoing vitrectomy and silicone oil tamponade.

Exclusion Criteria:

  • History of trauma
  • Presence of diabetic retinopathy
  • History of vein occlusion
  • Giant retinal tear
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Please refer to this study by its identifier: NCT00373282

Iran, Islamic Republic of
Hamid Ahmadieh,MD
Tehran, Iran, Islamic Republic of, 16666
Sponsors and Collaborators
Shahid Beheshti University of Medical Sciences
Principal Investigator: Hamid Ahmadieh, MD Ophthalmic Research Center of Shaheed Beheshti Medical University
  More Information Identifier: NCT00373282     History of Changes
Other Study ID Numbers: 8116 
Study First Received: September 7, 2006
Last Updated: October 11, 2006
Health Authority: Iran: Ethics Committee

Keywords provided by Shahid Beheshti University of Medical Sciences:
Retinal detachment
Silicone oil

Additional relevant MeSH terms:
Vitreoretinopathy, Proliferative
Eye Diseases
Retinal Diseases
Triamcinolone Acetonide
Triamcinolone diacetate
Triamcinolone hexacetonide
Anti-Inflammatory Agents
Enzyme Inhibitors
Hormones, Hormone Substitutes, and Hormone Antagonists
Immunologic Factors
Immunosuppressive Agents
Molecular Mechanisms of Pharmacological Action
Physiological Effects of Drugs processed this record on May 26, 2016