This site became the new on June 19th. Learn more.
Show more Menu IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu IMPORTANT: Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu
Give us feedback

The Effect of Cinnamon on HbA1c Among Adolescents With Type I Diabetes

This study has been completed.
Dartmouth College
Information provided by:
Dartmouth-Hitchcock Medical Center Identifier:
First received: August 31, 2006
Last updated: NA
Last verified: August 2006
History: No changes posted
the purpose of this study is to determine if cinnamon improves glucose control among adolescents with type 1 diabetes mellitus.

Condition Intervention Phase
Type 1 Diabetes Mellitus Drug: cinnamon Phase 2 Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double
Primary Purpose: Treatment
Official Title: The Effect of Cinnamon on HbA1c Among Adolescents With Type I Diabetes

Resource links provided by NLM:

Further study details as provided by Dartmouth-Hitchcock Medical Center:

Primary Outcome Measures:
  • HbA1c

Secondary Outcome Measures:
  • Total Daily Insulin
  • Carbohydrate/insulin dose
  • Hypoglycemic events
  • Compliance

Estimated Enrollment: 72
Study Start Date: October 2005
Estimated Study Completion Date: May 2006
Detailed Description:

Widespread achievement of glucose control remains an elusive goal for adolescents with Type 1 diabetes. Previous research has suggested that cinnamon may be effective at improving glucose control in type 2 diabetes. To date, no research has investigated the effect of cinnamon on type 1 diabetics. If the addition of a simple, natural, pill to a standard insulin regimen can significantly improve glucose control, the clinical implications would be substantial.

Comparison: Using a prospective, double-blind, placebo-controlled design, 72 adolescent type I diabetics were treated with cinnamon (1 gram/day) or an equivalent appearing placebo for 90 days. HbA1c, total daily insulin intake, and adverse events were recorded and compared between groups.


Ages Eligible for Study:   13 Years to 18 Years   (Child, Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  1. Diagnosis of Type 1 diabetes for > 18 months prior to enrollment,
  2. Age 13-18 years at the time of enrollment
  3. Presenting to the clinic for routine care,
  4. No hospital admissions for medical or psychiatric reasons in the 12 months prior to enrollment,
  5. Accessible by phone,
  6. Not pregnant.

Exclusion Criteria:

(1) Pregnant

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00371800

United States, New Hampshire
Dartmouth-Hitchcock Medical Center
Lebanon, New Hampshire, United States, 03756
Sponsors and Collaborators
Dartmouth-Hitchcock Medical Center
Dartmouth College
Principal Investigator: Samuel J Casella, MD Dartmouth-Hitchcock Medical Center
  More Information Identifier: NCT00371800     History of Changes
Other Study ID Numbers: 17648
Study First Received: August 31, 2006
Last Updated: August 31, 2006

Keywords provided by Dartmouth-Hitchcock Medical Center:
Type 1 Diabetes

Additional relevant MeSH terms:
Diabetes Mellitus
Diabetes Mellitus, Type 1
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases
Autoimmune Diseases
Immune System Diseases processed this record on September 19, 2017