Effect of Adjunctive Treatment With Arestin on the Subgingival Microflora in Patients With Moderate to Advanced Periodontitis
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Layout table for eligibility information
Ages Eligible for Study:
30 Years to 65 Years (Adult, Older Adult)
Sexes Eligible for Study:
Generalized moderate to advanced chronic periodontitis, five sites with probing depths of >5 mm in 5 non-adjacent interproximal spaces, excluding the distal of terminal teeth, at least 16 teeth excluding 3rd molars and implants
Allergy to tetracycline
Subjects with aggressive periodontitis
Acute necrotizing ulcerative gingivitis, or gross decay
Systemic conditions which could influence the course of periodontal disease (i.e, diabetes, autoimmune disease, etc)
Individuals requiring prophylactic antibiotics
Any periodontal therapy within the previous 3 months (excluding maintenance therapy)
Systemic or local antibiotic therapy within three months