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Trabeculectomy With MMC Versus Ahmed Glaucoma Implant for Treatment of Pediatric Aphakic Glaucoma

This study has been completed.
Information provided by:
Shahid Beheshti University of Medical Sciences Identifier:
First received: August 31, 2006
Last updated: October 6, 2006
Last verified: July 2003
In this randomized clinical trial we compare trabeculectomy with mitomycin-C (T+MMC) and Ahmed glaucoma implant (AGI) in treatment of aphakic glaucoma in children under 16 years of age.Complete and qualified success were defined as 5≤IOP≤21mmHg without and with medication respectively and we came to this point that; T+MMC and AGI are comparable in terms of success rate and complications in pediatric aphakic glaucoma.

Condition Intervention Phase
Pediatric Aphakic Glaucoma Procedure: trabeculectomy with mitomycin-C Phase 2 Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single
Primary Purpose: Treatment

Resource links provided by NLM:

Further study details as provided by Shahid Beheshti University of Medical Sciences:

Study Start Date: March 2004
Estimated Study Completion Date: November 2005

Ages Eligible for Study:   up to 16 Years   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • congenital cataract
  • history of cataract surgery
  • under 16 years old
  • Ocular pressure more than 21 mmHg

Exclusion Criteria:

  • interruption of the follow up before 6 month
  • Anterior segment dysgenesis
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Please refer to this study by its identifier: NCT00371072

Iran, Islamic Republic of
Ophthalmic Research Center
Tehran, Iran, Islamic Republic of, 16666
Sponsors and Collaborators
Shahid Beheshti University of Medical Sciences
Principal Investigator: Mohammad Pakravan, MD Ophthalmic Research Center of Shaheed Beheshti Medical University
  More Information Identifier: NCT00371072     History of Changes
Other Study ID Numbers: 8370
Study First Received: August 31, 2006
Last Updated: October 6, 2006

Keywords provided by Shahid Beheshti University of Medical Sciences:
Aphakic Glaucoma
trabeculectomy with mitomycin- C
Ahmed glaucoma implant

Additional relevant MeSH terms:
Ocular Hypertension
Eye Diseases
Antibiotics, Antineoplastic
Antineoplastic Agents
Alkylating Agents
Molecular Mechanisms of Pharmacological Action
Nucleic Acid Synthesis Inhibitors
Enzyme Inhibitors processed this record on September 21, 2017