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A Study of Meditation as a Treatment for Epilepsy

This study has been completed.
Information provided by (Responsible Party):
John Stern, University of California, Los Angeles Identifier:
First received: August 30, 2006
Last updated: July 20, 2016
Last verified: July 2016
Epileptic seizures may occur at times of stress and commonly increase life stress. This study will evaluate whether meditation improves seizure control and quality of life for individuals with uncontrolled epilepsy.

Condition Intervention
Epilepsy Behavioral: Meditation

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Treatment of Epilepsy by Meditation and Cultivation of Emotional Balance

Resource links provided by NLM:

Further study details as provided by John Stern, University of California, Los Angeles:

Primary Outcome Measures:
  • Seizure frequency [ Time Frame: 20 weeks ]
  • Quality of Life [ Time Frame: 20 weeks ]

Secondary Outcome Measures:
  • Mood [ Time Frame: 20 weeks ]
  • Affect [ Time Frame: 20 weeks ]
  • Anxiety [ Time Frame: 20 weeks ]
  • Sleep quality [ Time Frame: 20 weeks ]

Enrollment: 8
Study Start Date: May 2006
Study Completion Date: January 2008
Primary Completion Date: January 2008 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Meditation Behavioral: Meditation

Detailed Description:
Individuals who have uncontrolled epilepsy commonly experience disability, depression, anxiety and injuries from seizures. For such individuals, ideal treatments should improve quality of life through control of seizures and improved emotional state. Meditation with cultivation of emotional balance is known to improve emotional state and may also benefit seizure control in some individuals. In this study, individuals with uncontrolled epilepsy will receive detailed training in meditation to determine whether the training leads to improvements in seizure control and various measures of emotion and quality of life.

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • 6 or more seizures per month
  • ability to participate in meditation
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00370929

United States, California
Geffen School of Medicine at UCLA
Los Angeles, California, United States, 90095
Sponsors and Collaborators
University of California, Los Angeles
Principal Investigator: John Stern, MD University of California, Los Angeles
  More Information

Responsible Party: John Stern, Principal Investigator, University of California, Los Angeles Identifier: NCT00370929     History of Changes
Other Study ID Numbers: HSPC-06-03-001
Study First Received: August 30, 2006
Last Updated: July 20, 2016
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

Additional relevant MeSH terms:
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases processed this record on August 18, 2017